Results 21 to 30 of about 290,347 (229)

Biallelic mutations in UGDH cause congenital microcephaly. [PDF]

Genes Dis, 2023
Shu L, Xie G, Mei D, Xu R, Liu S, Xiao B, Li X, Xie Y, Mao X, Wang H.   +9 more
europepmc   +4 more sources

Association of arthrogryposis in neonates with microcephaly due to Zika virus - a case serie

Revista Brasileira de Saúde Materno Infantil
Introduction: in 2015 an increasing number of congenital microcephaly cases were associated to maternal infection due to Zika virus. Some of these patients presented other alterations and arthrogryposis was the most frequently found.
Ana Catarina Matos Ishigami Alvino, Luísa Rocha Medeiros de Mello, Jucille do Amaral Meneses Meira de Oliveira   +2 more
doaj   +2 more sources

Low CCL2 and CXCL8 Production and High Prevalence of Allergies in Children with Microcephaly Due to Congenital Zika Syndrome

Viruses, 2023
Congenital Zika Syndrome (CZS) is associated with an increased risk of microcephaly in affected children. This study investigated the peripheral dysregulation of immune mediators in children with microcephaly due to CZS.
Wallace Pitanga Bezerra, Anna Cláudia Calvielli Castelo Branco, Paulo Marcos Matta Guedes   +2 more
exaly   +3 more sources

Exome Sequencing Reveals Novel Variants and Expands the Genetic Landscape for Congenital Microcephaly. [PDF]

Genes (Basel), 2021
Congenital microcephaly causes smaller than average head circumference relative to age, sex and ethnicity and is most usually associated with a variety of neurodevelopmental disorders.
Dawidziuk M, Gambin T, Bukowska-Olech E, Antczak-Marach D, Badura-Stronka M, Buda P, Budzynska E, Castaneda J, Chilarska T, Czyzyk E, Eckersdorf-Mastalerz A, Fijak-Moskal J, Gieruszczak-Bialek D, Glodek-Brzozowska E, Goszczanska-Ciuchta A, Grzeszykowska-Podymniak M, Gurda B, Jakubiuk-Tomaszuk A, Jamroz E, Janeczko M, Jedlińska-Pijanowska D, Jurek M, Karolewska D, Kazmierczak A, Kleist T, Kochanowska I, Krajewska-Walasek M, Kufel K, Kutkowska-Kaźmierczak A, Lipiec A, Maksym-Gasiorek D, Materna-Kiryluk A, Mazurkiewicz H, Milewski M, Pavina-Guglas T, Pietrzyk A, Posmyk R, Pyrkosz A, Rudzka-Dybala M, Slezak R, Wisniewska M, Zalewska-Miszkurka Z, Szczepanik E, Obersztyn E, Bekiesinska-Figatowska M, Gawlinski P, Wiszniewski W.   +46 more
europepmc   +2 more sources

Prevalence of congenital microcephaly and its risk factors in an area at risk of Zika outbreaks. [PDF]

BMC Pregnancy Childbirth, 2021
Background: Prevalence of neonatal microcephaly in populations without Zika-epidemics is sparse. The study aimed to report baseline prevalence of congenital microcephaly and its relationship with prenatal factors in an area at risk of Zika outbreak ...
Shen S, Xiao W, Zhang L, Lu J, Funk A, He J, Tu S, Yu J, Yang L, Fontanet A, Bao W, Cheng KK, Qiu X.   +12 more
europepmc   +2 more sources

Proteomic profile in congenital microcephaly [PDF]

Annals of Human Genetics, 2021
Autosomal recessive primary microcephaly (MCPH) consists of a group of disorders characterized by microcephaly and intellectual disability. This study is essential to complement previous findings of MCPH as it helps clarify the role of different genes and proteins involved in the underlying pathophysiology of MCPH.
Ferih, Khaled Ramadan, Elsabagh, Ahmed Adel, Zaqout, Sami Ismail, Kaindl, Angela M   +3 more
openaire   +6 more sources

Spatiotemporal Analysis of the Population Risk of Congenital Microcephaly in Pernambuco State, Brazil. [PDF]

Int J Environ Res Public Health, 2020
Since an outbreak in Brazil, which started in 2015, Zika has been recognized as an important cause of microcephaly. The highest burden of this outbreak was in northeast Brazil, including the state of Pernambuco.
Alexander NDE, Souza WV, Rodrigues LC, Braga C, Sá A, Bezerra LCA, Turchi Martelli CM.   +6 more
europepmc   +2 more sources

Congenital Zika Infection and the Risk of Neurodevelopmental, Neurological, and Urinary Track Disorders in Early Childhood. A Systematic Review

Viruses, 2021
It was late 2015 when Northeast Brazil noticed a worrying increase in neonates born with microcephaly and other congenital malformations. These abnormalities, characterized by an abnormally small head and often neurological impairment and later termed ...
Evangelia Antoniou, Eirini Orovou, Paraskevi Eva Andronikidi, Christos Orovas, Nikolaos Rigas, Ermioni Palaska, Angeliki Sarella, Georgios Iatrakis, Chrysa Voyiatzaki   +8 more
doaj   +1 more source

Expanding the mutational spectrum of congenital microcephaly in Pakistani families. [PDF]

Front Genet
Autosomal recessive primary microcephaly (MCPH) is a genetically heterogeneous neurodevelopmental disorder characterized by a markedly reduced head circumference (−3 to −5 standard deviations) at birth, with relatively preserved brain architecture.
Farooq S, Asif M, Abbasi AA, Latif Z, Ku B, Makhdoom EUH, Shadab M, Khan MA, Muzammal M, Waqar R, Nisar R, Khan FS, Aslam S, Schweiger MR, Hussain MS.   +14 more
europepmc   +3 more sources

Congenital microcephaly unrelated to flavivirus exposure in coastal Kenya. [PDF]

Wellcome Open Res, 2019
Background: Zika virus (ZIKV) was first discovered in East Africa in 1947.  ZIKV has caused microcephaly in the Americas, but it is not known whether ZIKV is a cause of microcephaly in East Africa. Methods: We used surveillance data ...
Barsosio HC, Gitonga JN, Karanja HK, Nyamwaya DK, Omuoyo DO, Kamau E, Hamaluba MM, Nyiro JU, Kitsao BS, Nyaguara A, Mwakio S, Newton CR, Sang R, Wright D, Sanders EJ, Seale AC, Agoti CN, Berkley JA, Bejon P, Warimwe GM.   +19 more
europepmc   +4 more sources