Results 11 to 20 of about 22,857 (208)

The Unfolded Protein Response: A Key Player in Zika Virus-Associated Congenital Microcephaly [PDF]

Frontiers in Cellular Neuroscience, 2019
Zika virus (ZIKV) is a mosquito-borne virus that belongs to the Flaviviridae family, together with dengue, yellow fever, and West Nile viruses. In the wake of its emergence in the French Polynesia and in the Americas, ZIKV has been shown to cause ...
Christian Alfano, Ivan Gladwyn-Ng, Thérèse Couderc, Thérèse Couderc, Marc Lecuit, Marc Lecuit, Marc Lecuit, Laurent Nguyen   +7 more
doaj   +2 more sources

Prevalence and causes of congenital microcephaly in the absence of a Zika virus outbreak in southern Brazil

Jornal De Pediatria, 2019
Objective: The aim of this study was to identify the causes of congenital microcephaly in Rio Grande do Sul, a state in southern Brazil, where no ZIKV outbreak was detected, from December 2015 to December 2016, which was the period when ZIKV infection ...
Lavinia Schuler-Faccini, Maria TERESA Sanseverino   +1 more
exaly   +5 more sources

Microcephaly Resulting From Congenital Toxoplasmosis: What the Radiologist can Expect to See? A Case Report

Radiology Case Reports
Microcephaly is defined as an occipitofrontal head circumference two standard deviations (2SD) below average for age and sex, with severe microcephaly below three standard deviations (3SD).
Salma Marrakchi, Soumya El Graini, Allali Nazik   +2 more
exaly   +3 more sources

Congenital Microcephaly: A Debate on Diagnostic Challenges and Etiological Paradigm of the Shift from Isolated/Non-Syndromic to Syndromic Microcephaly [PDF]

Cells, 2023
Muhammad Sajid Hussain, Uzma Abdullah, Peter Nürnberg   +2 more
exaly   +2 more sources

Biallelic mutations in UGDH cause congenital microcephaly. [PDF]

Genes Dis, 2023
Shu L, Xie G, Mei D, Xu R, Liu S, Xiao B, Li X, Xie Y, Mao X, Wang H.   +9 more
europepmc   +4 more sources

Case Fatality Rate Related to Microcephaly Congenital Zika Syndrome and Associated Factors: A Nationwide Retrospective Study in Brazil †

Viruses, 2020
Background: The clinical manifestations of microcephaly/congenital Zika syndrome (microcephaly/CZS) have harmful consequences on the child’s health, increasing vulnerability to childhood morbidity and mortality. This study analyzes the case fatality rate
Barreto Ml, Moreno Rodrigues, Enny Paixao   +2 more
exaly   +3 more sources

Low CCL2 and CXCL8 Production and High Prevalence of Allergies in Children with Microcephaly Due to Congenital Zika Syndrome

Viruses, 2023
Congenital Zika Syndrome (CZS) is associated with an increased risk of microcephaly in affected children. This study investigated the peripheral dysregulation of immune mediators in children with microcephaly due to CZS.
Wallace Bezerra, Anna Claudia Branco, Paulo Marcos Matta Guedes   +2 more
exaly   +3 more sources

Congenital Zika syndrome: Growth, clinical, and motor development outcomes up to 36 months of age and differences according to microcephaly at birth

International Journal of Infectious Diseases, 2021
Background: Little is known regarding the developmental consequences of congenital Zika syndrome (CZS) without microcephaly at birth. Most previously published clinical series were descriptive and they had small sample sizes. Study design: We conducted a
Ricardo Khouri, Luciana Cavalcante Costa, Rosangela Batista   +2 more
exaly   +3 more sources

COLQ-mutant congenital myasthenic syndrome with microcephaly: A unique case with literature review

Translational Neuroscience, 2017
Congenital Myasthenic Syndrome (CMS) is a group of inherited neuromuscular junction disorders caused by defects in several genes. Clinical features include delayed motor milestones, recurrent respiratory illnesses and variable fatigable weakness.
Al-Mobarak Sulaiman Bazee, Al-Muhaizea Mohammad A.   +1 more
exaly   +2 more sources

Proteomic profile in congenital microcephaly [PDF]

Annals of Human Genetics, 2021
Autosomal recessive primary microcephaly (MCPH) consists of a group of disorders characterized by microcephaly and intellectual disability. This study is essential to complement previous findings of MCPH as it helps clarify the role of different genes and proteins involved in the underlying pathophysiology of MCPH.
Ferih, Khaled Ramadan, Elsabagh, Ahmed Adel, Zaqout, Sami Ismail, Kaindl, Angela M   +3 more
openaire   +6 more sources