Results 11 to 20 of about 22,740 (195)

Microcephaly Resulting From Congenital Toxoplasmosis: What the Radiologist can Expect to See? A Case Report

Radiology Case Reports
Microcephaly is defined as an occipitofrontal head circumference two standard deviations (2SD) below average for age and sex, with severe microcephaly below three standard deviations (3SD).
Salma Marrakchi, Allali Nazik, Soumya El Graini   +2 more
exaly   +3 more sources

Congenital Microcephaly: A Debate on Diagnostic Challenges and Etiological Paradigm of the Shift from Isolated/Non-Syndromic to Syndromic Microcephaly [PDF]

Cells, 2023
Maria Asif, Uzma Abdullah, Peter Nürnberg   +2 more
exaly   +2 more sources

Case Fatality Rate Related to Microcephaly Congenital Zika Syndrome and Associated Factors: A Nationwide Retrospective Study in Brazil †

Viruses, 2020
Background: The clinical manifestations of microcephaly/congenital Zika syndrome (microcephaly/CZS) have harmful consequences on the child’s health, increasing vulnerability to childhood morbidity and mortality. This study analyzes the case fatality rate
Maria Gloria Teixeira, Mauricio L Barreto, Giovanny V A Franca   +2 more
exaly   +3 more sources

Low CCL2 and CXCL8 Production and High Prevalence of Allergies in Children with Microcephaly Due to Congenital Zika Syndrome

Viruses, 2023
Congenital Zika Syndrome (CZS) is associated with an increased risk of microcephaly in affected children. This study investigated the peripheral dysregulation of immune mediators in children with microcephaly due to CZS.
Wallace P Bezerra, Amanda Costa Ayres Salmeron, Anna Cláudia Calvielli Castelo Branco   +2 more
exaly   +3 more sources

Congenital Zika syndrome: Growth, clinical, and motor development outcomes up to 36 months of age and differences according to microcephaly at birth

International Journal of Infectious Diseases, 2021
Background: Little is known regarding the developmental consequences of congenital Zika syndrome (CZS) without microcephaly at birth. Most previously published clinical series were descriptive and they had small sample sizes. Study design: We conducted a
Tamires Barradas Cavalcante, Marizélia Rodrigues Costa Ribeiro, Vanda Maria Ferreira Simöes   +2 more
exaly   +3 more sources

Congenital microcephaly: A diagnostic challenge during Zika epidemics

Travel Medicine and Infectious Disease, 2018
The multiple, wide and diverse etiologies of congenital microcephaly are complex and multifactorial. Recent advances in genetic testing have improved understanding of novel genetic causes of congenital microcephaly. The recent Zika virus (ZIKV) epidemic in Latin America has highlighted the need for a better understanding of the underlying pathological ...
Alvaro J Idrovo, Alfonso J Rodríguez-Morales, Alberto Paniz-Mondolfi   +2 more
exaly   +3 more sources

COLQ-mutant congenital myasthenic syndrome with microcephaly: A unique case with literature review

Translational Neuroscience, 2017
Congenital Myasthenic Syndrome (CMS) is a group of inherited neuromuscular junction disorders caused by defects in several genes. Clinical features include delayed motor milestones, recurrent respiratory illnesses and variable fatigable weakness.
Al-Mobarak Sulaiman Bazee, Al-Muhaizea Mohammad A.   +1 more
exaly   +2 more sources

Proteomic profile in congenital microcephaly [PDF]

Annals of Human Genetics, 2021
Autosomal recessive primary microcephaly (MCPH) consists of a group of disorders characterized by microcephaly and intellectual disability. This study is essential to complement previous findings of MCPH as it helps clarify the role of different genes and proteins involved in the underlying pathophysiology of MCPH.
Ferih, Khaled Ramadan, Elsabagh, Ahmed Adel, Zaqout, Sami Ismail, Kaindl, Angela M   +3 more
openaire   +6 more sources

Prevalence of microcephaly: the Latin American Network of Congenital Malformations 2010–2017

BMJ Paediatrics Open, 2021
Objective The Latin American Network of Congenital Malformations: ReLAMC was established in 2017 to provide accurate congenital anomaly surveillance. This study used data from ReLAMC registries to quantify the prevalence of microcephaly from 2010 to 2017
Helen Dolk, Boris Groisman, Joan Morris, Rosa Pardo, Elizabeth Limb, Iêda M Orioli, Adriana Benavides-Lara, María de la Paz Barboza-Arguello, Maria Aurora Canessa Tapia, Giovanny Vinícius Araújo de França, Jorge Holguin, Paula Margarita Hurtado-Villa, Marisol Ibarra Ramirez, Cecilia Mellado, Dania Maria Pastora Bucardo, Catherin Rodríguez, Ignacio Zarante   +16 more
doaj   +1 more source

Congenital microcephaly [PDF]

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, 2014
The underlying etiologies of genetic congenital microcephaly are complex and multifactorial. Recently, with the exponential growth in the identification and characterization of novel genetic causes of congenital microcephaly, there has been a consolidation and emergence of certain themes concerning underlying pathomechanisms.
Alcantara, Diana, O'Driscoll, Mark
openaire   +2 more sources