Results 31 to 40 of about 22,740 (195)
Congenital Zika Virus Syndrome: Microcephaly and Orofacial Anomalies
Life, 2023 The progressive reappearance of the Zika virus (ZIKV) infection since October 2013 and its circulation in >70 countries and territories (from French Polynesia to Brazil and other countries in the Americas, with sporadic spread in Europe and the East) has long been reported as a global public health emergency.
Gaetano Scotto +3 more
openaire +3 more sources
BMC Infectious Diseases, 2021 Background More than 5 years after the Zika virus (ZIKV) epidemic, Zika infection remains a major concern in regions with high Aedes infestation. The objectives of this study were (i) to identify clusters of ZIKV infection and microcephaly, and/or ...
Patrícia Silva Nunes +4 more
doaj +1 more source
Microcephaly in Neurometabolic Diseases
Children, 2022 Neurometabolic disorders are an important group of diseases that mostly occur in neonates and infants. They are mainly due to the lack or dysfunction of an enzyme or cofactors necessary for a specific biochemical reaction, which leads to a deficiency of ...
Wiktoria Kempińska +3 more
doaj +1 more source
Altered inhibition and excitation in neocortical circuits in congenital microcephaly [PDF]
Neurobiology of Disease, 2019 Congenital microcephaly is highly associated with intellectual disability. Features of autosomal recessive primary microcephaly subtype 3 (MCPH3) also include hyperactivity and seizures. The disease is caused by biallelic mutations in the Cyclin-dependent kinase 5 regulatory subunit-associated protein 2 gene CDK5RAP2.
Sami Zaqout +9 more
openaire +3 more sources
BMC Public Health, 2020 Background Although it is known that Zika virus (ZIKV) infection during pregnancy may lead to microcephaly in the fetus, the prognostic factors associated with this tragic disorder remain unclear.
Luciana Guerra Gallo +13 more
doaj +1 more source
Zika Virus RNA Replication and Persistence in Brain and Placental Tissue
Emerging Infectious Diseases, 2017 Zika virus is causally linked with congenital microcephaly and may be associated with pregnancy loss. However, the mechanisms of Zika virus intrauterine transmission and replication and its tropism and persistence in tissues are poorly understood.
Julu Bhatnagar +19 more
doaj +1 more source
Association of congenital Zika syndrome with dental alterations in children with microcephaly
PLoS ONE, 2022 The effects of congenital Zika syndrome (CZS) on the tooth development of infected children are not well known. The aim of this study was to analyze the association of CZS with dental alterations in children with microcephaly seen at a referral hospital ...
Patrícia Nóbrega Gomes +5 more
doaj
Scientific Reports, 2021 Not every neonate with congenital Zika virus (ZIKV) infection (CZI) is born with microcephaly. We compared inflammation mediators in CSF (cerebrospinal fluid obtained from lumbar puncture) between ZIKV-exposed neonates with/without microcephaly (cases ...
Gustavo C. Nascimento-Carvalho +9 more
doaj +1 more source
35 Individuals With HUWE1‐Related Neurodevelopmental Disorder and Suggested Clinical Evaluations
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X‐linked intellectual disability, including in the patients identified by Juberg, Marsidi, and ...
Mindy H. Li +25 more
wiley +1 more source
Microcephaly in South Brazil: Are cases of Congenital Zika Syndrome increasing in recent years?
Genetics and Molecular BiologyNortheast Brazil was the first region to detect a significant increase in babies born with microcephaly associated with prenatal zika virus infection in 2015.
Anna Pires Terra +12 more
doaj +1 more source