Results 51 to 60 of about 100,362 (316)

Real-world evidence of quadrivalent meningococcal conjugate vaccine safety in the United States: a systematic review

Human Vaccines & Immunotherapeutics, 2021
Two quadrivalent meningococcal conjugate vaccines (MenACWY) that prevent invasive meningococcal disease caused by N. meningitidis serogroups A, C, Y, and W have been licensed in the U.S. in the past 10–15 years.
Tracy a Becerra-Culqui, Lina S. Sy, Zendi Solano, Hung Fu Tseng   +3 more
doaj   +1 more source

Supplementary Figure from Preclinical Evaluation of IMGC936, a Next-Generation Maytansinoid-based Antibody–drug Conjugate Targeting ADAM9-expressing Tumors

, 2022
Supplementary Figure from Preclinical Evaluation of IMGC936, a Next-Generation Maytansinoid-based Antibody–drug Conjugate Targeting ADAM9-expressing ...
Jeff Hooley (15084369), Ying Li (15092440), Richard J. Gregory (15092479), Stuart W. Hicks (15092404), Marian Themeles (15092434), Jacquelynn Lucas (15092419), Kerstin W. Sinkevicius (15092407), Kerry A. McEachem (15092464), Nicholas C. Yoder (15092410), Valentina Ciccarone (15092461), Sergey Gorlatov (15092455), Paul A. Moore (15092473), Deryk Loo (15092485), Megan E. Fuller (15092422), Thomas Son (15092425), Lusiana Widjaja (15092452), Olga Ab (15087715), Thomas Chittenden (15092476), Francine Z. Chen (15092437), James Tamura (15092458), Bhaswati Barat (15092449), Scott Koenig (15092467), Michael Chiechi (15092443), Christopher Espelin (15092431), Jennifer G. Brown (15092416), Gundo Diedrich (15092413), Juniper A. Scribner (15092401), Jenny Lee (15092446), Ezio Bonvini (15092482), Anahita Dastur (15092428), Eric H. Westin (15092470)   +30 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Obtención de un conjugado peroxidasa-anti-antígeno de superficie del virus de la hepatitis B Obtention of a peroxidase-anti-hepatitis B virus surface antigen conjugate

Revista Cubana de Investigaciones Biomédicas, 2007
Se preparó y evaluó un conjugado para la detección del antígeno de superficie del virus de la hepatitis B por inmunoensayo enzimático tipo sandwich de doble anticuerpo.
Tammy Fernández Romero, Antonio González Griego, Antonio Melchor Rodríguez, Félix J. Fernández Acosta   +3 more
doaj  

Spectral tuning of 11-cis retinal in conjugation with Au14 cluster and concomitant effect on isomerization: A theoretical outlook

Journal of Photochemistry and Photobiology, 2021
The present study explores the optical properties of retinal molecules in presence of small gold cluster (Au14), where the cluster motifs are varied through Oh, D2h and C4v symmetries. The constructive interference of the transition dipole moments (TDMs)
Banita Sinha, Tamal Goswami, Satadal Paul, Anirban Misra   +3 more
doaj   +1 more source

Multi-serotype pneumococcal nasopharyngeal carriage prevalence in vaccine naïve Nepalese children, assessed using molecular serotyping.

, 2015
Invasive pneumococcal disease is one of the major causes of death in young children in resource poor countries. Nasopharyngeal carriage studies provide insight into the local prevalence of circulating pneumococcal serotypes.
Gurung, M, Kandasamy, Rama, Neelam Adhikari, David R Murdoch, Katherine A Gould, Murdoch, DR, Thapa, A, Adhikari, N, Hinds, Jason, Shrestha, S, Gould, Katherine A., Anushil Thapa, Kandasamy, R ; https://orcid.org/, Waldron, Denise E., Stephen Thorson, Rama Kandasamy, Waldron, DE, Gould, KA, Ndimah, S, Thorson, Stephen, Kelly, Dominic F., Shrijana Shrestha, Thorson, S, Dominic F Kelly, Meeru Gurung, Thapa, Anushil, Andrew J Pollard, Murdoch, David R., Ndimah, Susan, Shrestha, Shrijana, Denise E Waldron, Hinds, J, Pollard, Andrew J., Kandasamy, R, Adhikari, Neelam, Jason Hinds, Kelly, DF, Gurung, Meeru, Pollard, AJ, Pollard, Andrew, Susan Ndimah   +40 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Obtención de un conjugado peroxidasa-antígeno de superficie del virus de la hepatitis B Obtention of a peroxidase-hepatitis B virus surface antigen conjugate

Revista Cubana de Investigaciones Biomédicas, 2007
Se preparó un conjugado para la determinación de anticuerpos contra el antígeno de superficie del virus de la hepatitis B por inmunoensayo enzimático tipo sandwich de doble Ag. Se utilizó la peroxidasa, el antígeno de la vacuna cubana contra la hepatitis
Tammy Fernández Romero, Antonio González Griego, Antonio Melchor Rodríguez, Félix J. Fernández Acosta   +3 more
doaj  

Synthesis, conjugating capacity and biocompatibility evaluation of a novel amphiphilic polynorbornene

Designed Monomers and Polymers, 2020
Polynorbornenes, prepared by the ‘living’ and ‘controlled’ ring-opening metathesis polymerization (ROMP) method, have emerged as a stimuli-sensitive new class of polymer carriers.
Hengxi He, Bin Song, Guirong Qiu, Weixiang Wang, Haibin Gu   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source