Results 101 to 110 of about 11,641,221 (293)

A new hybrid conjugate gradient method of unconstrained optimization methods [PDF]

open access: yes, 2022
In this paper, we present a new hybrid method to solve a nonlinear unconstrained optimization problem by using conjugate gradient, which is a convex combination of Liu–Storey (LS) conjugate gradient method and Hager–Zhang (HZ) conjugate gradient method ...
Chenna Nasreddine   +2 more
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Programação paralela aplicada ao método N-Scheme para solução de problemas com o método de elementos finitos [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2012.Nesta tese é proposta uma nova técnica para resolução de problemas estáticos com o método de elementos ...
Eyng, Juliana
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

A Bayesian Conjugate Gradient Method [PDF]

open access: yes, 2019
A fundamental task in numerical computation is the solution of large linear systems. The conjugate gradient method is an iterative method which offers rapid convergence to the solution, particularly when an effective preconditioner is employed.
Ipsen, Ilse C.F.   +8 more
core   +2 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Efficient non-linear 3D electrical tomography reconstruction

open access: yes, 2001
Non-linear electrical tomography imaging can be performed efficiently if certain optimisations are applied to the computational reconstruction process. We present a 3D non-linear reconstruction algorithm based on a regularized conjugate gradient solver ...
Blott, B H   +7 more
core   +1 more source

Extension of Modified Polak-Ribière-Polyak Conjugate Gradient Method to Linear Equality Constraints Minimization Problems

open access: yesAbstract and Applied Analysis, 2014
Combining the Rosen gradient projection method with the two-term Polak-Ribière-Polyak (PRP) conjugate gradient method, we propose a two-term Polak-Ribière-Polyak (PRP) conjugate gradient projection method for solving linear equality constraints ...
Zhifeng Dai
doaj   +1 more source

An imperfect conjugate gradient algorithm [PDF]

open access: yes, 1982
summary:A new biorthogonalization algorithm is defined which does not depend on the step-size used. The algorithm is suggested so as to minimize the total error after $n$ steps if imperfect steps are used.
Sloboda, Fridrich
core   +1 more source

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