Results 241 to 250 of about 2,653,171 (296)

Harnessing microbial metabolism and nutrition to target the gut–mammary axis for better livestock production and health

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou   +29 more
wiley   +1 more source

A synthetic community promotes macadamia growth via root‐microbe interactions and systemic plant responses

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
We employed an 18‐month pot experiment and an integrated multi‐omics approach to elucidate the potential mechanisms underlying synthetic community (SynCom)‐mediated macadamia growth promotion. SynCom inoculation enhanced soil nitrogen cycling and potential nutrient (e.g., iron) acquisition.
Xiaofang Yao   +5 more
wiley   +1 more source

Bacterial indole‐3‐butyric acid promotes fish PUFA synthesis

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
Polyunsaturated fatty acids (PUFAs) are essential nutrients in aquatic products, yet the contribution of gut microbiota‐derived metabolites to PUFA biosynthesis remains largely unknown. In this study, a gut‐derived Bacillus strain was identified to enhance PUFA accumulation via indole‐3‐butyric acid (IBA) production.
Ruojing Li   +10 more
wiley   +1 more source

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

open access: yesInterdisciplinary Medicine, Volume 4, Issue 5, September 2026.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang   +13 more
wiley   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

open access: yesInterdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao   +7 more
wiley   +1 more source

Oxylipins‐Omics Combine With Single‐Molecule Analysis Identifies 13(S)‐HODE Positive Extracellular Vesicles as a Diagnostic Biomarker for AFP‐Negative Hepatocellular Carcinoma

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Our work identifies EV‐derived 13(S)‐HODE as a novel biomarker for HCC, establishes a single‐molecule platform for EV lipid analysis, and constructs a high‐performance diagnostic model by integrating multi‐dimensional data, offering new potential strategies for early monitoring and precise diagnosis of HCC.2 ABSTRACT Efficient diagnostic biomarkers ...
Yu Wang   +15 more
wiley   +1 more source

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