Conjugation-Based Genome Engineering in Deinococcus radiodurans [PDF]
Deinococcus radiodurans has become an attractive microbial platform for the study of extremophile biology and industrial bioproduction. To improve the genomic manipulation and tractability of this species, the development of tools for whole genome ...
Stephanie L. Brumwell (12206604) +9 more
core +1 more source
Site-directed Conjugation of Single-Stranded DNA to Affinity Proteins: Quantifying the Importance of Conjugation Strategy [PDF]
Affinity protein–oligonucleotide conjugates are increasingly being explored as diagnostic and therapeutic tools. Despite growing interest, these probes are typically constructed using outdated, non-selective chemistries, and little has been done to ...
Sarah, Duclos Ivetich +13 more
core +1 more source
Peptide-Protein Conjugation and Characterization to Develop Vaccines for Group A Streptococcus [PDF]
Peptide conjugates have been widely used for developing vaccines that prevent common bacterial infections for which peptides alone are either ineffective or provide only short-term protection. Among several carrier proteins, diphtheria toxoid and CRM197 (
Manisha Pandey +5 more
core +1 more source
Taming Unhindered Alkyl Azides by Intramolecular Hydrogen-Azide Interaction for Discriminative Conjugation onto Alkyl Diazides [PDF]
We report herein the unique reactivities of α-azido secondary acetamides (α-AzSAs) as minimal and unhindered azide structures. The NH–azide interaction in the α-AzSAs, supposed by DFT calculation, allowed selective conjugation in the presence of other ...
Koshiro, Maegawa +5 more
core +1 more source
AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugate Production [PDF]
The site-directed chemical conjugation of antibodies remains an area of great interest and active efforts within the antibody-drug conjugate (ADC) community.
Muneki, Isokawa +16 more
core +1 more source
Conjugation-Driven “Reverse Mars–van Krevelen”-Type Radical Mechanism for Low-Temperature C–O Bond Activation [PDF]
C–O bond activation on monofunctional catalysts (metals, carbides, and oxides) is challenging due to activity constraints imposed by energy scaling relationships.
Dionisios G. Vlachos (261715) +1 more
core +3 more sources
Novel self-transmissible plasmids were exogenously captured from environmental samples by triparental matings with pBBR1MCS-2 as a mobilizable plasmid and Pseudomonas resinovorans as a recipient.
Kosuke Yanagiya +13 more
doaj +1 more source
The nitrous acid depolymerization of chitosan enables the synthesis of singular chitosan oligosaccharides (COS) since their reducing-end unit is composed of 2,5-anhydro-d-mannofuranose (amf).
Maxence Coudurier +6 more
doaj +1 more source
The action of any group on itself by conjugation and the corresponding conjugacy relation play an important role in group theory. There have been several attempts to extend the notion of conjugacy to semigroups. In this paper, we present a new definition of conjugacy that can be applied to an arbitrary semigroup and it does not reduce to the universal ...
João Araújo +2 more
openaire +3 more sources
Optimisation of DSF and SOA based phase conjugators by incorporating noise-suppressing fibre gratings [PDF]
We compare the performance of dispersion-shifted-fibre (DSF) and semiconductor-optical-amplifier (SOA) based phase conjugators for a 10 Gb/s non-return-to-zero system with respect to conversion efficiency, noise figure and distortion.
Laming, R.I. +4 more
core +1 more source

