Results 11 to 20 of about 285,333 (315)
Conjugation-Based Genome Engineering in Deinococcus radiodurans
Deinococcus radiodurans has become an attractive microbial platform for the study of extremophile biology and industrial bioproduction. To improve the genomic manipulation and tractability of this species, the development of tools for whole genome ...
Stephanie L. Brumwell (12206604) +9 more
core +1 more source
Affinity protein–oligonucleotide conjugates are increasingly being explored as diagnostic and therapeutic tools. Despite growing interest, these probes are typically constructed using outdated, non-selective chemistries, and little has been done to ...
Sarah, Duclos Ivetich +13 more
core +1 more source
Cyanobacteria, the largest phylum of prokaryotes, perform oxygenic photosynthesis and are regarded as the ancestors of the plant chloroplast and the purveyors of the oxygen and biomass that shaped the biosphere.
Célia Chenebault +14 more
doaj +1 more source
The action of any group on itself by conjugation and the corresponding conjugacy relation play an important role in group theory. There have been several attempts to extend the notion of conjugacy to semigroups. In this paper, we present a new definition of conjugacy that can be applied to an arbitrary semigroup and it does not reduce to the universal ...
João Araújo +2 more
openaire +3 more sources
Novel self-transmissible plasmids were exogenously captured from environmental samples by triparental matings with pBBR1MCS-2 as a mobilizable plasmid and Pseudomonas resinovorans as a recipient.
Kosuke Yanagiya +13 more
doaj +1 more source
Peptide-Protein Conjugation and Characterization to Develop Vaccines for Group A Streptococcus
Peptide conjugates have been widely used for developing vaccines that prevent common bacterial infections for which peptides alone are either ineffective or provide only short-term protection. Among several carrier proteins, diphtheria toxoid and CRM197 (
Manisha Pandey +5 more
core +1 more source
The nitrous acid depolymerization of chitosan enables the synthesis of singular chitosan oligosaccharides (COS) since their reducing-end unit is composed of 2,5-anhydro-d-mannofuranose (amf).
Maxence Coudurier +6 more
doaj +1 more source
Natural Occurring and Engineered Enzymes for Peptide Ligation and Cyclization
The renaissance of peptides as prospective therapeutics has fostered the development of novel strategies for their synthesis and modification. In this context, besides the development of new chemical peptide ligation approaches, especially the use of ...
Timo Nuijens +5 more
doaj +1 more source
The global spread of antibiotic resistance has posed a serious threat to public healthcare and undermined decades of progress made in the fight against bacterial infections.
Yuan Liu +5 more
doaj +1 more source
The dispersal of mobile genetic elements and their gene cargo relies on type IV secretion systems (T4SS). In this work the ICEAfe1 Tra-type T4SS nanomachine, encoded in the publicly available genome of Acidithiobacillus ferrooxidans ATCC 23270TY, was ...
Rodrigo Flores-Ríos +9 more
doaj +1 more source

