Results 41 to 50 of about 286,248 (314)

Structural insights into the membrane-extracted dimeric form of the ATPase TraB from the Escherichia coli pKM101 conjugation system [PDF]

open access: yes, 2011
Background: Type IV secretion (T4S) systems are involved in secretion of virulence factors such as toxins or transforming molecules, or bacterial conjugation. T4S systems are composed of 12 proteins named VirB1-B11 and VirD4.
Veronique Receveur-Brechot   +5 more
core   +1 more source

Folic acid conjugated with serum albumin for nano- and submicron delivery systems for applications in therapy and diagnostics [PDF]

open access: yesExploration of Drug Science
Folic acid (FA) residue is a well-known and widely spread targeting ligand, or biovector, used as a component in engineering artificial nanosized and submicron particles (NSPs) to target various cells and treat a variety of diseases that are associated ...
Maria G. Gorobets   +5 more
doaj   +1 more source

Dominant Bacterial Phyla from the Human Gut Show Widespread Ability To Transform and Conjugate Bile Acids

open access: yesmSystems, 2021
Gut bacteria influence human physiology by chemically modifying host-synthesized primary bile acids. These modified bile acids, known as secondary bile acids, can act as signaling molecules that modulate host lipid, glucose, and energy metabolism and ...
L. N. Lucas   +7 more
doaj   +1 more source

A broad brush, global overview of bacterial sexuality [PDF]

open access: yes, 2011
Bacterial sexuality is confusing, even for experts! I used to be such an expert on one mechanism of sexuality, conjugation, but that was over 30 years ago.
Mark Achtman, Achtman, Mark
core   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei   +17 more
wiley   +1 more source

Proteotoxic stress reprograms the chromatin landscape of SUMO modification [PDF]

open access: yes, 2015
The small ubiquitin-like modifier 2 (SUMO-2) is required for survival when cells are exposed to treatments that induce proteotoxic stress by causing the accumulation of misfolded proteins.
Seifert, Anne   +3 more
core   +1 more source

Enzymatic Azido-GalNAc-Functionalized Silk Fibroin for Click Chemistry Conjugation [PDF]

open access: yes, 2021
Silk is a popular protein biomaterial that has been used for various purposes such as tissue scaffolding, textiles and hydrogels. Various methods for covalent conjugation of functional molecules such as small molecule sensors and enzymes have been ...
Packer, NH, Moh, ESX
core   +1 more source

Bacterial conjugation [PDF]

open access: yes, 2011
Bacteria can transfer genetic material, and thus drug resistance, to other bacteria via conjugationEducação Superior::Ciências da Saúde ...
Howard Hughes Medical Institute (HHMI)
core   +2 more sources

A Polymorphic Gene within the Mycobacterium smegmatis esx1 Locus Determines Mycobacterial Self-Identity and Conjugal Compatibility

open access: yesmBio, 2022
Mycobacteria mediate horizontal gene transfer (HGT) by a process called distributive conjugal transfer (DCT) that is mechanistically distinct from oriT-mediated plasmid transfer.
R. R. Clark   +4 more
doaj   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen   +21 more
wiley   +1 more source

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