Results 31 to 40 of about 319,697 (204)

Plasmid conjugation genes.

, 2023
(A) Plasmid pMS7163B conjugation genes as defined by TraDIS. Log2(fold-change–FC) values for insertions in each gene between the pre- and post-conjugation libraries are displayed against pMS7163B.
Minh-Duy Phan (198730), Mark A. Schembri (9330815), Nguyen Thi Khanh Nhu (12872563), Zheng Jie Lian (16425811), David L. Paterson (124677), Steven J. Hancock (12872557)   +5 more
core   +1 more source

Foodborne Microbial Communities as Potential Reservoirs of Antimicrobial Resistance Genes for Pathogens: A Critical Review of the Recent Literature

Microorganisms, 2023
Antimicrobial resistance (AMR) is a global and increasing threat to human health. Several genetic determinants of AMR are found in environmental reservoirs, including bacteria naturally associated with widely consumed fermented foods.
Paola Zinno, Giuditta Perozzi, Chiara Devirgiliis   +2 more
doaj   +1 more source

Reducing Antigenicity and Improving Antioxidant Capacity of β-Lactoglobulin through Covalent Interaction with Six Flavonoids

Foods, 2023
β-lactoglobulin (β-LG) is a pivotal nutritional and functional protein. However, its application is limited by its antigenicity and susceptibility to oxidation.
Pei Pu, Zhifen Deng, Lang Chen, Han Yang, Guizhao Liang   +4 more
doaj   +1 more source

Structural and Biochemical Analysis of OrfG: The VirB8-like Component of the Conjugative Type IV Secretion System of ICESt3 From Streptococcus thermophilus

Frontiers in Molecular Biosciences, 2021
Conjugative transfer is a major threat to global health since it contributes to the spread of antibiotic resistance genes and virulence factors among commensal and pathogenic bacteria.
Julien Cappele, Abbas Mohamad Ali, Nathalie Leblond-Bourget, Sandrine Mathiot, Tiphaine Dhalleine, Sophie Payot, Martin Savko, Claude Didierjean, Frédérique Favier, Badreddine Douzi   +9 more
doaj   +1 more source

Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in sumo pathways [PDF]

, 2010
Canonical ubiquitin-like proteins (UBLs) such as ubiquitin, Sumo, NEDD8, and ISG15 are ligated to targets by E1-E2-E3 multienzyme cascades. The Sumo cascade, conserved among all eukaryotes, regulates numerous biological processes including protein ...
Miller, D.J., Asad M Taherbhoy, Schulman, B.A., Darcie J Miller, Steven N Seyedin, Huang Danny T., Wang, J., Kobe, B., Steven N. Seyedin, Seyedin Steven N., David W. Miller, Miller David W., Darcie J. Miller, Hunt Harold W., Miller, D.W., Taherbhoy, A.M., Danny T. Huang, Brenda A. Schulman, Miller Darcie J., Danny T Huang, Wang Jing, Harold W. Hunt, Harold W Hunt, Asad M. Taherbhoy, Schulman Brenda A., Jing Wang, Huang, D.T., Taherbhoy Asad M., David W Miller, Hunt, H.W., Seyedin, S.N., Brenda A Schulman   +31 more
core   +2 more sources

Capture of mobile genetic elements following intercellular conjugation promotes the production of ST11-KL64 CR-hvKP

Microbiology Spectrum
Sequence type (ST)11 carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) can cause life-threatening infections and is therefore of global concern.
Shanshan Huang, Dan Dan Wei, Hanxu Hong, Si Chen, Lin-Ping Fan, Qi-Sen Huang, Fang-Ling Du, Tian-Xin Xiang, Ping Li, Wei Zhang, La-Gen Wan, Yang Liu   +11 more
doaj   +1 more source

Conjugation-Driven “Reverse Mars–van Krevelen”-Type Radical Mechanism for Low-Temperature C–O Bond Activation

, 2016
C–O bond activation on monofunctional catalysts (metals, carbides, and oxides) is challenging due to activity constraints imposed by energy scaling relationships.
Dionisios G. Vlachos (261715), Alexander V. Mironenko (1634152)   +1 more
core   +2 more sources

Variation on a theme; an overview of the Tn916 / Tn1545 family of mobile genetic elements in the oral and nasopharyngeal streptococci.

Frontiers in Microbiology, 2014
The oral and nasopharyngeal streptococci are a major part of the normal microbiota in humans. Most human associated streptococci are considered commensals however a small number of them are pathogenic, causing a wide range of diseases including oral ...
Francesco eSantoro, Morgana Eli Vianna, Adam Paul Roberts   +2 more
doaj   +1 more source

Folic acid conjugated with serum albumin for nano- and submicron delivery systems for applications in therapy and diagnostics [PDF]

Exploration of Drug Science
Folic acid (FA) residue is a well-known and widely spread targeting ligand, or biovector, used as a component in engineering artificial nanosized and submicron particles (NSPs) to target various cells and treat a variety of diseases that are associated ...
Maria G. Gorobets, Anna V. Toroptseva, Madina I. Abdullina, Vadim S. Pokrovsky, Derenik S. Khachatryan, Anna V. Bychkova   +5 more
doaj   +1 more source

Dominant Bacterial Phyla from the Human Gut Show Widespread Ability To Transform and Conjugate Bile Acids

mSystems, 2021
Gut bacteria influence human physiology by chemically modifying host-synthesized primary bile acids. These modified bile acids, known as secondary bile acids, can act as signaling molecules that modulate host lipid, glucose, and energy metabolism and ...
L. N. Lucas, K. Barrett, R. L. Kerby, Q. Zhang, L. E. Cattaneo, D. Stevenson, F. E. Rey, D. Amador-Noguez   +7 more
doaj   +1 more source