Results 21 to 30 of about 311,139 (302)

Direct Conjugation of Resveratrol on Hydrophilic Gold Nanoparticles: Structural and Cytotoxic Studies for Biomedical Applications

open access: yesNanomaterials, 2020
Strongly hydrophilic gold nanoparticles (AuNPs), functionalized with citrate and L-cysteine, were synthetized and used as Resveratrol (RSV) vehicle to improve its bioavailability.
Iole Venditti   +7 more
doaj   +1 more source

Characterizing conjugative plasmids from an antibiotic-resistant dataset for use as broad-host delivery vectors

open access: yesFrontiers in Microbiology, 2023
Human microbiome engineering is increasingly proposed as a way to modulate health outcomes. However, one of the current limitations to engineering microbial communities in situ is delivery of a genetic payload for introducing or modifying genes.
Héctor G. Loyola Irizarry   +1 more
doaj   +1 more source

A purple odyssey: synthesis and structure of 3-amino-4-hydroxy-6-oxocyclohexa-2,4-dien-1-iminium chloride monohydrate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
In the cation of the title hydrated molecular salt, C6H7N2O2+·Cl−·H2O, the six-membered ring shows unequal bond lengths consistent with delocalization of electrons over two separate 6π systems with single bonds between them.
M. John Plater, William T. A. Harrison
doaj   +1 more source

Differential Requirement for the Cell Wall Integrity Sensor Wsc1p in Diploids Versus Haploids

open access: yesJournal of Fungi, 2021
The primary role of the Cell Wall Integrity Pathway (CWI) in Saccharomyces cerevisiae is monitoring the state of the cell wall in response to general life cycle stresses (growth and mating) and imposed stresses (temperature changes and chemicals). Of the
Allison E. Hall   +2 more
doaj   +1 more source

On Functions with a Conjugate [PDF]

open access: yesAnnales de l'Institut Fourier, 2015
Harmonic functions of two variables are exactly those that admit a conjugate, namely a function whose gradient has the same length and is everywhere orthogonal to the gradient of the original function. We show that there are also partial differential equations controlling the functions of three variables that admit a conjugate.
Baird, Paul, Eastwood, Michael
openaire   +3 more sources

Peptide-Protein Conjugation and Characterization to Develop Vaccines for Group A Streptococcus

open access: yes, 2021
Peptide conjugates have been widely used for developing vaccines that prevent common bacterial infections for which peptides alone are either ineffective or provide only short-term protection. Among several carrier proteins, diphtheria toxoid and CRM197 (
Manisha Pandey   +5 more
core   +1 more source

AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugate Production [PDF]

open access: yes, 2023
The site-directed chemical conjugation of antibodies remains an area of great interest and active efforts within the antibody-drug conjugate (ADC) community.
Muneki, Isokawa   +16 more
core   +2 more sources

Taming Unhindered Alkyl Azides by Intramolecular Hydrogen-Azide Interaction for Discriminative Conjugation onto Alkyl Diazides [PDF]

open access: yes, 2021
We report herein the unique reactivities of α-azido secondary acetamides (α-AzSAs) as minimal and unhindered azide structures. The NH–azide interaction in the α-AzSAs, supposed by DFT calculation, allowed selective conjugation in the presence of other ...
Koshiro, Maegawa   +5 more
core   +2 more sources

Foodborne Microbial Communities as Potential Reservoirs of Antimicrobial Resistance Genes for Pathogens: A Critical Review of the Recent Literature

open access: yesMicroorganisms, 2023
Antimicrobial resistance (AMR) is a global and increasing threat to human health. Several genetic determinants of AMR are found in environmental reservoirs, including bacteria naturally associated with widely consumed fermented foods.
Paola Zinno   +2 more
doaj   +1 more source

Reducing Antigenicity and Improving Antioxidant Capacity of β-Lactoglobulin through Covalent Interaction with Six Flavonoids

open access: yesFoods, 2023
β-lactoglobulin (β-LG) is a pivotal nutritional and functional protein. However, its application is limited by its antigenicity and susceptibility to oxidation.
Pei Pu   +4 more
doaj   +1 more source

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