Results 21 to 30 of about 286,248 (314)

Natural Occurring and Engineered Enzymes for Peptide Ligation and Cyclization

open access: yesFrontiers in Chemistry, 2019
The renaissance of peptides as prospective therapeutics has fostered the development of novel strategies for their synthesis and modification. In this context, besides the development of new chemical peptide ligation approaches, especially the use of ...
Timo Nuijens   +5 more
doaj   +1 more source

Correlation between Exogenous Compounds and the Horizontal Transfer of Plasmid-Borne Antibiotic Resistance Genes

open access: yesMicroorganisms, 2020
The global spread of antibiotic resistance has posed a serious threat to public healthcare and undermined decades of progress made in the fight against bacterial infections.
Yuan Liu   +5 more
doaj   +1 more source

The Type IV Secretion System of ICEAfe1: Formation of a Conjugative Pilus in Acidithiobacillus ferrooxidans

open access: yesFrontiers in Microbiology, 2019
The dispersal of mobile genetic elements and their gene cargo relies on type IV secretion systems (T4SS). In this work the ICEAfe1 Tra-type T4SS nanomachine, encoded in the publicly available genome of Acidithiobacillus ferrooxidans ATCC 23270TY, was ...
Rodrigo Flores-Ríos   +9 more
doaj   +1 more source

Direct Conjugation of Resveratrol on Hydrophilic Gold Nanoparticles: Structural and Cytotoxic Studies for Biomedical Applications

open access: yesNanomaterials, 2020
Strongly hydrophilic gold nanoparticles (AuNPs), functionalized with citrate and L-cysteine, were synthetized and used as Resveratrol (RSV) vehicle to improve its bioavailability.
Iole Venditti   +7 more
doaj   +1 more source

Characterizing conjugative plasmids from an antibiotic-resistant dataset for use as broad-host delivery vectors

open access: yesFrontiers in Microbiology, 2023
Human microbiome engineering is increasingly proposed as a way to modulate health outcomes. However, one of the current limitations to engineering microbial communities in situ is delivery of a genetic payload for introducing or modifying genes.
Héctor G. Loyola Irizarry   +1 more
doaj   +1 more source

Photoreversible Ultrafast Dynamics of Ring Opening and Increased Conjugation under Spatial Confinement [PDF]

open access: yes, 2023
Isomerization through stereochemical changes and modulation in bond order conjugation are processes that occur ubiquitously in diverse chemical systems and for pho- tochromic spirocompounds, it imparts them their functionality as phototransformable ...
Stuart A., Hayes   +6 more
core   +1 more source

Synthetic vaccines targeting Mincle through conjugation of trehalose dibehenate [PDF]

open access: yes, 2022
The covalent fusion of immunostimulatory adjuvants to immunogenic antigens is a promising strategy for the development of effective synthetic vaccines for infectious diseases.
Ismanto, Hendra S   +8 more
core   +1 more source

A purple odyssey: synthesis and structure of 3-amino-4-hydroxy-6-oxocyclohexa-2,4-dien-1-iminium chloride monohydrate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
In the cation of the title hydrated molecular salt, C6H7N2O2+·Cl−·H2O, the six-membered ring shows unequal bond lengths consistent with delocalization of electrons over two separate 6π systems with single bonds between them.
M. John Plater, William T. A. Harrison
doaj   +1 more source

Differential Requirement for the Cell Wall Integrity Sensor Wsc1p in Diploids Versus Haploids

open access: yesJournal of Fungi, 2021
The primary role of the Cell Wall Integrity Pathway (CWI) in Saccharomyces cerevisiae is monitoring the state of the cell wall in response to general life cycle stresses (growth and mating) and imposed stresses (temperature changes and chemicals). Of the
Allison E. Hall   +2 more
doaj   +1 more source

On Functions with a Conjugate [PDF]

open access: yesAnnales de l'Institut Fourier, 2015
Harmonic functions of two variables are exactly those that admit a conjugate, namely a function whose gradient has the same length and is everywhere orthogonal to the gradient of the original function. We show that there are also partial differential equations controlling the functions of three variables that admit a conjugate.
Baird, Paul, Eastwood, Michael
openaire   +3 more sources

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