Results 81 to 90 of about 186,611 (326)

Conditions for State and Control Constraint Activation in Coordination of Connected and Automated Vehicles

open access: yes, 2020
Connected and automated vehicles (CAVs) provide the most intriguing opportunity to reduce pollution, energy consumption, and travel delays. In earlier work, we addressed the optimal coordination of CAVs using Hamiltonian analysis.
Mahbub, A M Ishtiaque   +1 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Cooperative Lane-Changing Optimisation of Connected and Autonomous Vehicles in Freeway Merging Area

open access: yesPromet (Zagreb)
In freeway merging areas, vehicles exhibit flexibility in lane-changing manoeuvres to facilitate merging. However, the lack of effective communication among vehicles leads to inadequate coordination between mainline and ramp vehicles at the merge point ...
Xuling LIU, Xiaoning ZHANG
doaj   +1 more source

Predictive Path Following and Collision Avoidance of Autonomous Connected Vehicles

open access: yesAlgorithms, 2020
This paper considers nonlinear model predictive control for simultaneous path-following and collision avoidance of connected autonomous vehicles. For each agent, a nonlinear bicycle model is used to predict a sequence of the states and then optimize them
Mohamed Abdelaal, Steffen Schön
doaj   +1 more source

A Review of Car-Following Models and Modeling Tools for Human and Autonomous-Ready Driving Behaviors in Micro-Simulation

open access: yesSmart Cities, 2021
The platform of a microscopic traffic simulation provides an opportunity to study the driving behavior of vehicles on a roadway system. Compared to traditional conventional cars with human drivers, the car-following behaviors of autonomous vehicles (AVs)
Hafiz Usman Ahmed, Ying Huang, Pan Lu
doaj   +1 more source

Ethical and Social Aspects of Self-Driving Cars

open access: yes, 2018
As an envisaged future of transportation, self-driving cars are being discussed from various perspectives, including social, economical, engineering, computer science, design, and ethics.
Dodig-Crnkovic, Gordana   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Microscopic Simulation of Heterogeneous Traffic Flow on Multi-Lane Ring Roads and Highways

open access: yesApplied Sciences
In the connected and autonomous vehicle (CAV) environment, vehicles with different levels of automation are being deployed on public roads. Most research focuses on traffic flow simulation for a single vehicle type, while there are few studies on the ...
Haizhen Li, Yongfeng Ju
doaj   +1 more source

Regulatory and Technical Constraints: An Overview of the Technical Possibilities and Regulatory Limitations of Vehicle Telematic Data

open access: yesSensors, 2021
A telematics device is a vehicle instrument that comes preinstalled by the vehicle manufacturer or can be added later. The device records information about driving behavior, including speed, acceleration, and turning force.
Kevin McDonnell   +5 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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