Results 61 to 70 of about 179,061 (285)
, 2019 A fundamental challenge in autonomous vehicles is adjusting the steering angle at different road conditions. Recent state-of-the-art solutions addressing this challenge include deep learning techniques as they provide end-to-end solution to predict ...
Fallah, Yaser P. +3 more
core +1 more source
PAsCAL D3.2 Connected and Autonomous Vehicle
, 2021 This publication is produced in the PAsCAL project which has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No ...
openaire +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
PCM: A Positioning Calibration Mechanism for Connected Autonomous Vehicles
IEEE Access, 2020 Connected autonomous driving is considered as a potential way to improve traffic safety. However, when positioning information is delivered through network, the network time delay could result in additional positioning errors, which has been proved by ...
Yuhao Ling +4 more
doaj +1 more source
Smart Cities, 2021 The platform of a microscopic traffic simulation provides an opportunity to study the driving behavior of vehicles on a roadway system. Compared to traditional conventional cars with human drivers, the car-following behaviors of autonomous vehicles (AVs)
Hafiz Usman Ahmed, Ying Huang, Pan Lu
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
CPS architecture design for urban roadway intersections based on MBSE
Journal of Intelligent and Connected VehiclesWith the rapid growth of urbanization and the increasing demand for transportation, urban traffic congestion has become a hindrance to individuals’ travel experience.
Chen Wang +6 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source