Results 101 to 110 of about 993,171 (249)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Modeling and optimization control of SOEC with flexible adjustment capabilities
Scientific ReportsDue to the random fluctuations in power experienced by high-temperature green electric hydrogen production systems, further deterioration of spatial distribution characteristics such as temperature, voltage/current, and material concentration inside the ...
Yaqing He +6 more
doaj +1 more source
Recognizing and Mitigating Canine Stress in Human–Canine Interaction Research: Proposed Guidelines
AnimalsThe research into human–canine interactions (HCIs) has grown substantially, yet limited attention has focused on the welfare of canines involved, particularly pet dogs owned by volunteer participants.
Simone B. Sidel +3 more
doaj +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Energy Conversion and Management: XThis paper proposes a novel operational model enabling multi-type energy sources to participate in electricity markets, alongside a value distribution mechanism for flexible resources based on the Vickrey-Clarke-Groves (VCG) theory.
Yufa Qin +3 more
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Scientific ReportsThe increasing scale of wind power access to the grid makes it important to identify weak links in the system to prevent major outages. In order to analyze the vulnerability of grid nodes, this paper proposes a dynamic comprehensive evaluation method ...
Mingzhu Yan +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source