Results 71 to 80 of about 104,879 (300)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Defining the mobility range of a hinge-type connection using molecular dynamics and metadynamics.
PLoS ONE, 2020 A designed disulfide-rich β-hairpin peptide that dimerizes spontaneously served as a hinge-type connection between proteins. Here, we analyze the range of dynamics of this hinge dimer with the aim of proposing new applications for the DNA-encodable ...
Philip Horx, Armin Geyer
doaj +1 more source
On semistable principal bundles over a complex projective manifold, II
, 2008 Let (X, \omega) be a compact connected Kaehler manifold of complex dimension d and E_G a holomorphic principal G-bundle on X, where G is a connected reductive linear algebraic group defined over C. Let Z (G) denote the center of G.
A. Ramanathan +13 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Дифференциальная геометрия многообразий фигур, 2019 This research is realized by Cartan — Laptev method (with prolongations and scopes, moving frame and exterior forms). In this paper we consider a space П of centered m-planes (a space of all centered planes of the dimension m). This space is considered
Е. Belova, O. Belova
doaj +1 more source
Minimizers of higher order gauge invariant functionals
, 2015 We introduce higher order variants of the Yang-Mills functional that involve $(n-2)$th order derivatives of the curvature. We prove coercivity and smoothness of critical points in Uhlenbeck gauge in dimensions $\mathrm{dim}M\le 2n$.
Gastel, Andreas, Scheven, Christoph
core +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
General Relativity with a Positive Cosmological Constant Λ as a Gauge Theory
Axioms, 2019 In this paper, we show that the general relativity action (and Lagrangian) in recent Einstein⁻Palatini formulation is equivalent in four dimensions to the action (and Langrangian) of a gauge field.
Marta Dudek, Janusz Garecki
doaj +1 more source
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source