Results 71 to 80 of about 226,986 (311)
FEBS Letters, EarlyView.This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause +2 more
wiley +1 more source
About differential equations of the curvature tensors of a fundamental group and affine connections
Дифференциальная геометрия многообразий фигур, 2019 The principal bundle is considered, the base of which is an n-dimensional smooth manifold, and the typical fiber is an r-fold Lie group. Structure equations for the forms of the fundamental group and affine connections are given, each of which ...
N. Ryazanov
doaj +1 more source
Functoriality of Principal Bundles and Connections
, 2019 Perhaps the most important contribution of gauge theory to general mathematics is to point out the importance of association functors. Emphasizing category theory we characterize association functors by two of their natural properties and use this characterization to establish an equivalence between the category of principal bundles and a suitably ...
Moncada, Gustavo Amilcar Saldaña +1 more
openaire +2 more sources
FEBS Letters, EarlyView.The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva +1 more
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Double Principal Bundles [PDF]
Journal of Geometry and Physics, 170 (2021), 104354, 2016 We define double principal bundles (DPBs), for which the frame bundle of a double vector bundle, double Lie groups and double homogeneous spaces are basic examples. It is shown that a double vector bundle can be realized as the associated bundle of its frame bundle. Also dual structures, gauge transformations and connections in DPBs are investigated.
arxiv +1 more source
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Lietuvos Matematikos RinkinysIn this article we define the canonical forms on the principal bundle of holonomic frames of order r, give structure equations for these forms and determine the connection of order r.
Kazimeras Navickis
doaj +1 more source
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Pseudo-Sasakian manifolds endowed with a contact conformal connection
International Journal of Mathematics and Mathematical Sciences, 1986 Pseudo-Sasakian manifolds M˜(U,ξ,η˜,g˜) endowed with a contact conformal connection are defined.
Vladislav V. Goldberg, Radu Rosca
doaj +1 more source