Results 11 to 20 of about 335,564 (245)

Effect of Nigella sativa oil extracts on inflammatory and oxidative stress markers in Behcet’s disease: A randomized, double-blind, placebo-controlled clinical trial [PDF]

Avicenna Journal of Phytomedicine, 2020
Objective: Behcet's disease (BD) is a chronic inflammatory disorder characterized by recurrent oral and genital aphthous ulcers, uveitis and skin lesions. Oxidative stress and inflammation have important role in the pathogenesis of BD.
Shahrzad Amizadeh, Nadereh Rashtchizadeh, Alireza Khabbazi, Amir Ghorbanihaghjo, Ali-Asghar Ebrahimi, Amir-Mansour Vatankhahc, Aida Malek Mahdavi, Mohsen Taghizadeh   +7 more
doaj   +1 more source

Exploring metabolism in scleroderma reveals opportunities for pharmacological intervention for therapy in fibrosis

Frontiers in Immunology, 2022
BackgroundRecent evidence has indicated that alterations in energy metabolism play a critical role in the pathogenesis of fibrotic diseases. Studies have suggested that ‘metabolic reprogramming’ involving the glycolysis and oxidative phosphorylation ...
Isabella Gomes Cantanhede, Isabella Gomes Cantanhede, Huan Liu, Huan Liu, Huan Liu, Vestaen Balbuena Rodriguez, Xu Shiwen, Voo H. Ong, Christopher P. Denton, Markella Ponticos, Guo Xiong, José Luiz Lima-Filho, David Abraham, Jeries Abu-Hanna, Jan-Willem Taanman   +14 more
doaj   +1 more source

Prospective assessment of cardiovascular risk parameters in patients with rheumatoid arthritis

Cardiovascular Ultrasound, 2018
Background The study presents a prospective follow-up assessment of cardiovascular (CV) risk parameters in patients with rheumatoid arthritis (RA) in comparison with control subjects. Methods The study group consisted of 41 RA patients.
Bożena Targońska-Stępniak, Mariusz Piotrowski, Robert Zwolak, Anna Drelich-Zbroja, Maria Majdan   +4 more
doaj   +1 more source

Microangiopathic antiphospholipid syndrome (MAPS) in the course of undifferentiated connective tissue disease

Journal of Medical Science, 2014
Introduction. The microangiopathic antiphospholipid syndrome (MAPS) is a subset of APS comprising those patients presenting with thrombotic microangiopathy and demonstrable antiphospholipid antibodies. Renal involvement occurs frequently in the course of
Bożena Targońska-Stępniak, Ewa Wielosz, Maria Majdan   +2 more
doaj   +1 more source

Neuro‐Sjögren: Uncommon or underestimated problem?

Brain and Behavior, 2020
Objectives Sjögren's syndrome (SS) is a chronic inflammatory disease with an autoimmune background with possible complications from peripheral (PNS) and central nervous system (CNS).
Marta Jaskólska, Magdalena Chylińska, Anna Masiak, Mariusz Siemiński, Marcin Ziętkiewicz, Zenobia Czuszyńska, Żaneta Smoleńska, Zbigniew Zdrojewski   +7 more
doaj   +1 more source

Viability of Periosteal Tissue Obtained Postmortem

Cell Transplantation, 1999
Periosteal autografts have the potential to regenerate articular cartilage defects, but this potential is limited by the patient's age. Allograft transplantation from a young donor to an older recipient might bypass this limitation.
Shawn W. O'driscoll Ph.D., M.D., Borna Meisami, Yasushi Miura, James S. Fitzsimmons   +3 more
doaj   +1 more source

Boswellia frereana suppresses HGF-mediated breast cancer cell invasion and migration through inhibition of c-Met signalling

Journal of Translational Medicine, 2018
Background Hepatocyte growth factor (HGF) plays a pivotal role in breast cancer cell motility, invasion and angiogenesis. These pro-metastatic events are triggered through HGF coupling and activation of the c-Met receptor.
Christian Parr, Ahmed Y. Ali
doaj   +1 more source

Usefulness in daily practice of the Systemic Lupus Erythematosus Disease Activity Index 2000 scale and the Systemic Lupus Erythematosus Disease Activity Score index for assessing the activity of systemic lupus erythematosus

Rheumatology
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by high hetero­geneity of clinical manifestations and an uncertain prognosis. Although the mortality rate due to SLE has decreased significantly in recent decades, there is still a
Dorota Suszek, Maciej Dubaj, Karol Bigosiński, Aleksandra Dembowska, Marcin Kaniewski, Wiktoria Sielwanowska, Bartosz Skierkowski, Izabela Dzikowska, Julia Sieczka, Maria Majdan   +9 more
doaj   +1 more source

Stressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware, Colter K. Clayton, Fang Wang, Sedigheh Mirzaei, Kyla Shelton, Tara M. Brinkman, Victoria Willard, Katianne M. Howard Sharp, Kevin Krull, Lindsay F. Schwartz, Melissa M. Hudson, Gregory T. Armstrong, Kirsten K. Ness, Rachel T. Webster   +13 more
wiley   +1 more source

Association study between immune-related miRNAs and mixed connective tissue disease

Arthritis Research & Therapy, 2021
Background Mixed connective tissue disease (MCTD) is a rare condition that is distinguished by the presence of specific U1-RNP antibodies. Information about its etiopathology and diagnostics is still unclear.
Barbara Stypińska, Aleksandra Lewandowska, Anna Felis-Giemza, Marzena Olesińska, Agnieszka Paradowska-Gorycka   +4 more
doaj   +1 more source