Results 31 to 40 of about 4,769,883 (431)

Oral administration of pyrophosphate inhibits connective tissue calcification

open access: yesEMBO Molecular Medicine, 2017
Various disorders including pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI), which are caused by inactivating mutations in ABCC6 and ENPP1, respectively, present with extensive tissue calcification due to reduced ...
D. Dedinszki   +12 more
semanticscholar   +1 more source

Prospective assessment of cardiovascular risk parameters in patients with rheumatoid arthritis

open access: yesCardiovascular Ultrasound, 2018
Background The study presents a prospective follow-up assessment of cardiovascular (CV) risk parameters in patients with rheumatoid arthritis (RA) in comparison with control subjects. Methods The study group consisted of 41 RA patients.
Bożena Targońska-Stępniak   +4 more
doaj   +1 more source

Microangiopathic antiphospholipid syndrome (MAPS) in the course of undifferentiated connective tissue disease

open access: yesJournal of Medical Science, 2014
Introduction. The microangiopathic antiphospholipid syndrome (MAPS) is a subset of APS comprising those patients presenting with thrombotic microangiopathy and demonstrable antiphospholipid antibodies. Renal involvement occurs frequently in the course of
Bożena Targońska-Stępniak   +2 more
doaj   +1 more source

Neuro‐Sjögren: Uncommon or underestimated problem?

open access: yesBrain and Behavior, 2020
Objectives Sjögren's syndrome (SS) is a chronic inflammatory disease with an autoimmune background with possible complications from peripheral (PNS) and central nervous system (CNS).
Marta Jaskólska   +7 more
doaj   +1 more source

Viability of Periosteal Tissue Obtained Postmortem

open access: yesCell Transplantation, 1999
Periosteal autografts have the potential to regenerate articular cartilage defects, but this potential is limited by the patient's age. Allograft transplantation from a young donor to an older recipient might bypass this limitation.
Shawn W. O'driscoll Ph.D., M.D.   +3 more
doaj   +1 more source

Studies on the treatment of malignant tumors with fibroblast-inhibiting agent. II. Effects of chloro­quine on animal tumors [PDF]

open access: yes, 1963
Based on our original concept, a fibroblast-inhibiting agent, chloroquine, was used against various animal tumors. Among transplanted animal tumors, the drug was most effective on relatively connective tissue-rich Bashford and Brown-Pearce tumors, as ...
Hiraki, Kiyoshi, Kimura, Ikuro
core   +1 more source

Boswellia frereana suppresses HGF-mediated breast cancer cell invasion and migration through inhibition of c-Met signalling

open access: yesJournal of Translational Medicine, 2018
Background Hepatocyte growth factor (HGF) plays a pivotal role in breast cancer cell motility, invasion and angiogenesis. These pro-metastatic events are triggered through HGF coupling and activation of the c-Met receptor.
Christian Parr, Ahmed Y. Ali
doaj   +1 more source

Association study between immune-related miRNAs and mixed connective tissue disease

open access: yesArthritis Research & Therapy, 2021
Background Mixed connective tissue disease (MCTD) is a rare condition that is distinguished by the presence of specific U1-RNP antibodies. Information about its etiopathology and diagnostics is still unclear.
Barbara Stypińska   +4 more
doaj   +1 more source

Differential tissue sparing of FLASH ultra high dose rates: an {\it in-silico} study [PDF]

open access: yesarXiv, 2022
Purpose: To propose a theory for the differential tissue sparing of FLASH ultra high dose rates (UHDR) through inter-track reaction-diffusion mechanism. Methods: We calculate the time-evolution of particle track-structures using a system of coupled reaction-diffusion equations on a random network designed for molecular transport in porous and ...
arxiv  

Collective cell migration of epithelial cells driven by chiral torque generation [PDF]

open access: yesPhys. Rev. Research 2, 043326 (2020), 2019
Various multicellular tissues show chiral morphology. Experimental studies have shown this can originate from cell chirality. However, no theory has been proposed to connect the cellular chiral torque and multicellular chiral morphogenesis. We propose a model of confluent tissue dynamics with cellular chiral torque.
arxiv   +1 more source

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