The role of the gastrointestinal tract in the pathogenesis of rheumatic diseases [PDF]
, 2016 Dysregulation of the intestinal epithelial barrier in genetically susceptible individuals may lead to both intestinal and extraintestinal autoimmune disorders.
CICCIA, Francesco +3 more
core +1 more source
Annals of the Rheumatic Diseases, 2020 Interstitial lung diseases (ILDs), which can arise from a broad spectrum of distinct aetiologies, can manifest as a pulmonary complication of an underlying autoimmune and connective tissue disease (CTD-ILD), such as rheumatoid arthritis-ILD and systemic ...
P. Spagnolo +9 more
semanticscholar +1 more source
Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials [PDF]
, 2013 Rationale Clinical trial design in interstitial lung diseases (ILDs) has been hampered by lack of consensus on appropriate outcome measures for reliably assessing treatment response.
Antoniou, K +40 more
core +1 more source
Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
, 1996 To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E. +2 more
core +1 more source
Autoantibodies Associated With Connective Tissue Diseases: What Meaning for Clinicians?
Frontiers in Immunology, 2018 Connective tissue diseases (CTDs) such as systemic lupus erythematosus, systemic sclerosis, myositis, Sjögren’s syndrome, and rheumatoid arthritis are systemic diseases which are often associated with a challenge in diagnosis.
K. Didier +6 more
semanticscholar +1 more source
Carotid Artery Tortuosity Is Associated with Connective Tissue Diseases
American Journal of Neuroradiology, 2019 BACKGROUND AND PURPOSE: There is a general assumption in the cerebrovascular literature that there is an association between carotid artery tortuosity and connective tissues disease; however, this has not been firmly established.
John P. Welby +8 more
semanticscholar +1 more source
The role of endothelin-1 in pulmonary arterial hypertension. [PDF]
, 2014 Pulmonary arterial hypertension (PAH) is a rare but debilitating disease, which if left untreated rapidly progresses to right ventricular failure and eventually death. In the quest to understand the pathogenesis of this disease differences in the profile,
Chester, AH, Yacoub, MH
core +1 more source
Prospective assessment of cardiovascular risk parameters in patients with rheumatoid arthritis
Cardiovascular Ultrasound, 2018 Background The study presents a prospective follow-up assessment of cardiovascular (CV) risk parameters in patients with rheumatoid arthritis (RA) in comparison with control subjects. Methods The study group consisted of 41 RA patients.
Bożena Targońska-Stępniak +4 more
doaj +1 more source
Journal of Medical Science, 2014 Introduction. The microangiopathic antiphospholipid syndrome (MAPS) is a subset of APS comprising those patients presenting with thrombotic microangiopathy and demonstrable antiphospholipid antibodies. Renal involvement occurs frequently in the course of
Bożena Targońska-Stępniak +2 more
doaj +1 more source
Neuro‐Sjögren: Uncommon or underestimated problem?
Brain and Behavior, 2020 Objectives Sjögren's syndrome (SS) is a chronic inflammatory disease with an autoimmune background with possible complications from peripheral (PNS) and central nervous system (CNS).
Marta Jaskólska +7 more
doaj +1 more source