Results 41 to 50 of about 320,293 (286)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Ocular involvement in rheumatic diseases

Rheumatology, 2023
Rheumatic diseases are associated with a significant decline in quality of life, which is not only related to the progression of the underlying disease but also to the development of coexisting conditions.
Iwona Dankiewicz- Fares, Daniel Jeka, Tacjana Barczyńska   +2 more
doaj   +1 more source

Роль дисплазії сполучної тканини в розвитку рецидиву генітального пролапсу [PDF]

, 2003
В статье приводится анализ данных, посвященных влиянию дисплазии соединительной ткани на развитие рецидива генитального пролапса. За период с 2003 по 2011 год было обследовано и прооперировано 600 гинекологических пациентов с признаками ...
Потапов, В.О., Банахевич, Р.М., Золотарьов, Д.Л., Акимова, К.Б., Єчин, А.В.   +4 more
core  

A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]

, 1994
Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Bahn, Rebecca S., Dutton, Charyl M., Heufelder, Armin E., Sarkar, Gobinda   +3 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Analytical and numerical analyses of the micromechanics of soft fibrous connective tissues

, 2012
State of the art research and treatment of biological tissues require accurate and efficient methods for describing their mechanical properties. Indeed, micromechanics motivated approaches provide a systematic method for elevating relevant data from the ...
A Menzel, AD Freed, AN Gent, D Ambrosi, D Balzani, DE Kiousis, G deBotton, G deBotton, G deBotton, G deBotton, G deBotton, G Shmuel, GA Holzapfel, GA Holzapfel, GA Holzapfel, GA Holzapfel, GA Holzapfel, GA Holzapfel, Gal deBotton, H Chen, I Hariton, I Hariton, J Humphrey, J Stålhand, JD Humphrey, JD Humphrey, JD Humphrey, JD Humphrey, JF Eberth, L Figueiredo Borges de, LA Taber, M Agoras, M Brun, N Gundiah, N Triantafyllidis, NC Avery, O Lopez-Pamies, P Mortier, P Ponte Castañeda, R Hill, RM Nerem, RW Ogden, S Rudykh, Tal Oren, V Alastrué, Y Lanir, YC Fung   +46 more
core   +1 more source

Mast cell subsets and their functional modulation by the Acanthocheilonema viteae product ES-62 [PDF]

, 2013
ES-62, an immunomodulator secreted by filarial nematodes, exhibits therapeutic potential in mouse models of allergic inflammation, at least in part by inducing the desensitisation of Fc휀RI-mediated mast cell responses.
Al-Riyami, Lamyaa, Ball, Dimity, Bell, Kara, Coates, Michelle, Harnett, Margaret, Harnett, William, Rzepecka, Justyna, Tay, Hwee Kee   +7 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Challenging in leprosy relapse with antiphospholipid syndrome diagnosis: A case report

Clinical Case Reports
Key Clinical Message Infectious diseases like leprosy can cause antiphospholipid antibodies, leading to blood clots. Clinicians should consider this for patients with unusual thrombotic events and prior infectious disease history.
Sousan Kolahi, Leyla Ghadakchi, Amirreza Jabbaripour Sarmadian, Hamideh Azimi, Mehdi Jafarpour, Amirreza Khalaji   +5 more
doaj   +1 more source