Results 51 to 60 of about 1,447,658 (298)
Structural Connectivity Alterations in Operculo-Insular Epilepsy
Brain Sciences, 2021 Operculo-insular epilepsy (OIE) is an under-recognized condition that can mimic temporal and extratemporal epilepsies. Previous studies have revealed structural connectivity changes in the epileptic network of focal epilepsy.
Sami Obaid +11 more
doaj +1 more source
Resting state connectivity and cognitive performance in adults with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy [PDF]
, 2016 Cognitive impairment is an inevitable feature of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), affecting executive function, attention and processing speed from an early stage.
Cullen, Breda +8 more
core +1 more source
Notre Dame Journal of Formal Logic, 1991 The authors investigate a calculus of individuals based on a primitive notion of connectedness. They show that their system of axioms leads to complete orthocomplemented lattices whereas the extension of their system to the Clarke system leads to complete atomless Boolean algebras [see also \textit{B. Clarke}, ibid. 26, 61-75 (1985; Zbl 0597.03005)].
Biacino, Loredana, Gerla, Giangiacomo
openaire +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Assaying Mechanonociceptive Behavior in Drosophila Larvae
Bio-Protocol, 2018 Drosophila melanogaster larvae have been extensively used as a model to study the molecular and cellular basis of nociception. The larval nociceptors, class IV dendritic arborization (C4da) neurons, line the body wall of the animal and respond to various
Nina Hoyer +3 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The Connectivity Order of Links [PDF]
, 2008 We associate at each link a connectivity space which describes its splittability properties. Then, the notion of order for finite connectivity spaces results in the definition of a new numerical invariant for links, their connectivity order. A section of
Dugowson, Stéphane
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Learning from volcanic eruptions: Co-production of knowledge at Merapi and Kelud, Indonesia
JàmbáThe increasing frequency and intensity of volcanic disasters present major challenges for rural communities, particularly in terms of recovery and the restoration of environmental conditions post-crisis.
Nuzul Solekhah +9 more
doaj +1 more source
Lessons learned: Symbiotic autonomous robot ecosystem for nuclear environments
IET Cyber-systems and Robotics, 2023 Nuclear facilities have a regulatory requirement to measure radiation levels within Post Operational Clean Out (POCO) around nuclear facilities each year, resulting in a trend towards robotic deployments to gain an improved understanding during nuclear ...
Daniel Mitchell +35 more
doaj +1 more source