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Pulpal upregulation of connexin 43 during pulpitis
Clinical Oral Investigations, 2020Connexins are building blocks of membranous channels that form gap junctions and hemichannels. These channels are essential portals for information exchange and coordination during inflammation. Pathologic levels of these conduits may result in excessive inflammation and collateral destruction.
Wen Yi Lim +2 more
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Alterations of Connexin 43 in the Diabetic Rat Heart
2006In the streptozotocin-induced diabetic rat heart, a decrease in the conductivity and suppression of electrical cell-to-cell coupling has been observed. To clarify this mechanism, the present study was performed to investigate the gap junction connexin 43 (Cx43) using immunohistochemistry, immunoblot, electron-microscopic analyses.
Hai, Lin +3 more
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Role of Connexin 43 in Sertoli Cells of Testis
Annals of the New York Academy of Sciences, 2007Abstract: Connexin 43 (CX43, also known as GJA1) is the predominant testicular gap‐junction protein. In the seminiferous epithelium, gap junctions occur between adjacent Sertoli cells and between Sertoli and germ cells. The specific role of CX43 in Sertoli cell has been difficult to study because of the neonatal lethality of the Cx43 global knockout ...
Santhi, Sridharan +3 more
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Connexin 43 and Mitochondria in Cardiovascular Health and Disease
2017Connexin 43 (Cx43) is the major connexin protein in ventricular cardiomyocytes. Six Cx43 proteins assemble into so-called hemichannels at the sarcolemma and opposing hemichannels form gap junctions, which allow the passage of small molecules and electrical current flow between adjacent cells.
Kerstin, Boengler, Rainer, Schulz
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Redistribution of connexin 43 during cell division
Cell Biology International, 2016AbstractGap junction channels, once clustered into gap junction plaques, allow communication of essential metabolites between cells. Gap junction plaques have been reported to be lost from the cell surface during cell division. The mechanism involved in this loss of gap junction plaques during mitosis is unclear, but we hypothesize that an ...
Oluseyi A, Vanderpuye +2 more
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GJA1 (Connexin 43) and the Oculodentodigital Syndrome
2008Abstract Oculodentodigital syndrome (ODD; OMIM 164200) is a congenital disorder that is characterized by abnormalities of the face, eyes, dentition, and limbs (Fig. 173–1). ODD is inherited as an autosomal dominant trait and displays high penetrance but variable expression (Fig. 173–1).
Rebecca J Richardson, Michael J Dixon
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Cytomembrane Trafficking Pathways of Connexin 26, 30, and 43
International Journal of Molecular Sciences, 2023Yu Sun, Tu Lei
exaly
Mitochondrial connexin 43 hemichannels
Journal of Molecular and Cellular Cardiology, 2007Elisabet Miro-Casas +10 more
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Function of Connexin-43 in Macrophages
International Journal of Molecular Sciences, 2021Lilian Salm, Guido Beldi
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