Results 121 to 130 of about 75,295 (332)
Decreased Expression of Connexin 43 Blunts the Progression of Experimental GN.
Journal of the American Society of Nephrology, 2017 GN refers to a variety of renal pathologies that often progress to ESRD, but the molecular mechanisms underlying this progression remain incompletely characterized.
Panagiotis Kavvadas +10 more
semanticscholar +1 more source
Neuroprotection, EarlyView.Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng +9 more
wiley +1 more source
Connexin 46 and Connexin 50 in Selenite Cataract
Ophthalmic Research, 2005 The purpose of this work was to determine if the lens gap junction proteins connexin 46 (Cx46) and connexin 50 (Cx50) were altered with the development of selenite-induced cataract. Cataracts were induced in young Sprague-Dawley rats with a single subcutaneous injection of sodium selenite; age-matched uninjected rats served as controls.
openaire +3 more sources
Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System. [PDF]
, 2019 Mammalian cardiac Purkinje fibers (PFs) are specified from ventricular trabecular myocardium during mid-gestation and undergo limited proliferation before assuming their final form.
Evangelista, Melissa +5 more
core +2 more sources
HepaCAM associates with connexin 43 and enhances its localization in cellular junctions
Scientific Reports, 2016 HepaCAM (GlialCAM) is frequently deleted in carcinomas, and reintroduction of hepaCAM into transformed cell lines reduces cellular growth and induces senescence.
Meihui Wu, M. C. Moh, H. Schwarz
semanticscholar +1 more source
Involvement of gap junction channels in the pathophysiology of migraine with aura
Frontiers in Physiology, 2014 Migraine is a common, recurrent and disabling primary headache disorder with a genetic component which affects up to 20 % of the population. One third of all patients with migraine experiences aura, a focal neurological disturbance that manifests itself ...
Denis eSarrouilhe +2 more
doaj +1 more source
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Increased hours of cochlear implant (CI) use have been shown to improve auditory and speech recognition outcomes in children with hearing loss. However, the impact of hours of CI use over time on patient‐reported functional hearing skills is unknown.
Lacey Magee +3 more
wiley +1 more source
Connexin 43 plays a role in pulmonary vascular reactivity in mice [PDF]
, 2018 Pulmonary arterial hypertension (PAH) is a chronic condition characterized by vascular remodeling and increased vaso-reactivity. PAH is more common in females than in males (~3:1).
Andrew Shaw +11 more
core +1 more source
Frontiers in Cellular Neuroscience, 2015 Pannexin2 (Panx2) is the largest of three members of the pannexin proteins. Pannexins are topologically related to connexins and innexins, but serve different functional roles than forming gap junctions.
Daniela eBoassa +4 more
doaj +1 more source
MiR‐1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion
Environmental Toxicology, EarlyView.ABSTRACT MicroRNA‐1 (miR‐1) is a conserved microRNA that is highly expressed in skeletal and cardiac muscle tissues. Moreover, miR‐1 regulates genes and has critical roles in cell migration and invasion. Downregulation of miR‐1 has been found in many pathologies of numerous organs, including the lungs.
Maricica Pacurari +2 more
wiley +1 more source