Results 111 to 120 of about 29,751 (231)
Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases
Comprehensive Physiology, Volume 16, Issue 4, August 2026.Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal +2 more
wiley +1 more source
Yin Yang 1 Specifically Supports the Development of Olig2 Positive Cerebellar Astrocytes
Glia, Volume 74, Issue 8, August 2026.Cerebellar Olig2 positive astrocytes are most abundant in the cerebellar nuclei. Cerebellar astrocytes expressing Olig2 have unique gene expression profiles. Yin Yang 1 specifically supports the development of astrocytes expressing Olig2. Deletion of YY1 during development increases numbers of astrocytes expressing Olig2 but hinders their ...
Masoumeh Zarei‐Kheirabadi +9 more
wiley +1 more source
Serine Ameliorates Cadmium‐Induced Testicular Injury by Regulating the PGAM1/PHGDH Signaling Pathway
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.Serine mitigates cadmium‐induced testicular injury in mice by inhibiting the PGAM1/PHGDH pathway, restoring ion homeostasis and glycolysis, and relieving oxidative stress, inflammation, fibrosis, and apoptosis. ABSTRACT Cadmium (Cd) is a widespread environmental contaminant that impairs male reproductive function; however, the metabolic mechanisms ...
Xueru Wang +8 more
wiley +1 more source
Membrane‐Associated Biomolecules for Synthetic Cell Signalling
ChemBioChem, Volume 27, Issue 13, 14 July 2026.Membrane‐associated proteins and nucleic acids are transforming synthetic cell communication, unlocking applications in biosensing, therapeutics, and tissue engineering. This review explores how these biomolecules enable complementary strategies for cell tethering, vesicle generation and fusion, signal transmission, and signal transduction.
Chelsea Dack +3 more
wiley +1 more source
Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
Advanced Healthcare Materials, Volume 15, Issue 27, 17 July 2026.We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
Advanced Healthcare Materials, Volume 15, Issue 27, 17 July 2026.Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse +9 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.In this study, we explored the mechanisms for the therapeutic effects of TMZ and CoQ10 on myocarditis using network pharmacology, molecular docking, and molecular dynamics simulations. Our findings identified core targets of TMZ and CoQ10 treatment of myocarditis; the five core targets included EGFR, MMP9, PPARG, AKT1, and CASP3.
Ximing Chen +6 more
wiley +1 more source
Glia, Volume 74, Issue 7, July 2026.Astrocytes are key sensors and transducers of biomechanical stimuli within the central nervous system. Astrocyte development is highly dependent on mechanical stimuli such as surrounding tissue stiffness and biomechanical strain. Mechanosensory pathways including integrins, connexins and pannexins, and mechanosensitive channels regulate astrocyte ...
Ana N. Strat +3 more
wiley +1 more source