Results 121 to 130 of about 29,751 (231)
ABSTRACT Background and Aims Cardiovascular diseases (CVDs), such as heart failure (HF), myocardial ischemic‐reperfusion injury (MIRI), and myocardial infarction (MI), are defined as one of the most known causes of mortality and morbidity worldwide, responsible for 30% of global death rate.
Reza Arefnezhd +10 more
wiley +1 more source
Connexin 26 in Hearing Health and Disease: StructuralFoundations, Mutation Mechanisms, and Therapeutic Perspectives. [PDF]
Qiu W, Schneider K, Guo Y.
europepmc +1 more source
ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li +4 more
wiley +1 more source
Gap Junction-Mediated Communication in Melanoma: From Tumor Progression to Treatment Response. [PDF]
Massoud J +6 more
europepmc +1 more source
Seeing Invisible Oligomers: Rethinking α‐Synuclein Pathology Through Proximity Ligation Assay
Abstract Parkinson's disease (PD) and multiple system atrophy are defined by α‐synuclein (αSYN)‐positive inclusions – Lewy bodies (LBs) and glial cytoplasmic inclusions – yet mounting evidence indicates that these inclusions represent only a fraction of disease‐relevant pathology.
Hiroaki Sekiya +3 more
wiley +1 more source
Connexin-43-Mediated Gap Junction Coupling Between Adipocytes Regulates Norepinephrine-Induced Ca<sup>2+</sup> Responses in Perivascular Adipose Tissue. [PDF]
Kim AR +5 more
europepmc +1 more source
Abstract Objective To assess the prevalence of the GJB2 c.35delG mutation among Moroccan patients with nonsyndromic sensorineural hearing loss (NSHL) and compare it with frequencies reported in other North African populations. Study Design Retrospective cohort study. Setting Multidisciplinary tertiary care hearing loss genetics clinic.
El Mostafa Salman +10 more
wiley +1 more source
Editorial: Pannexin and connexin signaling in cell death and tissue health and disease
Marc Mesnil +2 more
doaj +1 more source
Astrocytic connexins in alcohol use disorder: mechanisms of neuroinflammation and therapeutic potential. [PDF]
Imafidon E +4 more
europepmc +1 more source
ABSTRACT Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects
Tali Czarnowicki +6 more
wiley +1 more source

