Results 41 to 50 of about 195,400 (281)
Air-Stimulated ATP Release from Keratinocytes Occurs through Connexin Hemichannels [PDF]
, 2013 Cutaneous ATP release plays an important role in both epidermal stratification and chronic pain, but little is known about ATP release mechanisms in keratinocytes that comprise the epidermis.
Albrecht, Phillip J. +5 more
core +5 more sources
Connexin Expression in Human Minor Salivary Glands: An Immunohistochemical Microscopy Study
Molecules, 2022 Connexins (Cxs) are transmembrane proteins involved in the formation of hemichannels and gap junctions (GJs). GJs are involved in various physiological functions, including secretion in glandular tissue. It has been demonstrated that Cx26, Cx32, and Cx43
Alessandra Falleni +11 more
doaj +1 more source
A Human-Derived Monoclonal Antibody Targeting Extracellular Connexin Domain Selectively Modulates Hemichannel Function [PDF]
, 2019 Connexin hemichannels, which are plasma membrane hexameric channels (connexons) composed of connexin protein protomers, have been implicated in a host of physiological processes and pathological conditions. A number of single point pathological mutations
Buratto, Damiano +12 more
core +1 more source
Cardiac mitochondrial connexin 43 regulates apoptosis [PDF]
Biochemical and Biophysical Research Communications, 2006 Connexin 43 (Cx43) is thought to be present largely in the plasma membrane and its function solely to provide low resistance electrical connection between myocytes. A recent report suggested the presence of Cx43 in the mitochondria as well. We confirmed the presence of Cx43 in the mitochondria isolated from adult rat ventricles with the Cx43 ...
Farida Goubaeva +5 more
openalex +4 more sources
Biomedicines, 2023 Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and internal organs. Although its pathogenesis is not fully understood, connexins (Cxs) and pannexins (Panx) could be involved in the process of fibrosis. We analyzed
Berna Pavic +5 more
doaj +1 more source
Cx43 channels and signaling via IP3/Ca2+, ATP, and ROS/NO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells [PDF]
, 2020 Radiotherapeutic treatment consists of targeted application of radiation beams to a tumor but exposure of surrounding healthy tissue is inevitable.
Bultynck, Geert +10 more
core +1 more source
Gap junction proteins and their role in spinal cord injury [PDF]
, 2015 © 2015 Tonkin, Mao, O'Carroll, Nicholson, Green, Gorrie and Moalem-Taylor. Gap junctions are specialized intercellular communication channels that are formed by two hexameric connexin hemichannels, one provided by each of the two adjacent cells.
Gorrie, CA +6 more
core +2 more sources
Connexin 43 Upregulation in Mouse Lungs during Ovalbumin-Induced Asthma. [PDF]
PLoS ONE, 2015 Connexin (Cx)-based gap junction channels play important roles in the inflammatory response. Cx43 is involved in the pathogenesis of some lung diseases such as acute lung injury. However, the Cx43 expression in asthma is unclear. In the present study, we
Yin Yao +9 more
doaj +1 more source
Signatures, sums of hermitian squares and positive cones on algebras with involution [PDF]
Electron. Res. Announc. Math. Sci. 25 (2018), 16-26, 2017 We provide a coherent picture of our efforts thus far in extending real algebra and its links to the theory of quadratic forms over ordered fields in the noncommutative direction, using hermitian forms and "ordered" algebras with involution.
arxiv +1 more source
Южно-Российский онкологический журнал, 2023 Purpose of the study. Evaluation of the expression of immunohistochemical tumor markers Ki-67, b-catenin, Bcl-2, P53, connexin 32 and connexin 43 when using 2-(6,8-dimethyl-5-nitro-4-chloroquinoline-2-yl)-5,6,7-trichloro-1,3-tropolone in mice with ...
E. F. Komarova +11 more
doaj +1 more source