Results 41 to 50 of about 377,682 (288)

Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome. [PDF]

, 2019
Introns are a prevalent feature of eukaryotic genomes, yet their origins and contributions to genome function and evolution remain mysterious. In budding yeast, repression of the highly transcribed intron-containing ribosomal protein genes (RPGs ...
Ares, Manuel, Donohue, John Paul, Igel, Haller, Katzman, Sol, Munding, Elizabeth M, Perriman, Rhonda J, Shelansky, Robert, Shiue, Lily, Talkish, Jason   +8 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Connectivity, neutral theories and the assessment of species vulnerability to global change in temperate estuaries [PDF]

, 2013
One of the main adaptation strategies to global change scenarios, aiming to preserve ecosystem functioning and biodiversity, is to maximise ecosystem resilience.
Albaina, A., Aranburu, A., Borja, Á., Chust, G., Diekmann, O.E., Diekmann, O.E., Franco, J., Garmendia, J.M., Iriondo, M., Muxika, I., Rendo, F., Rodríguez, J.G., Ruiz-Larrañaga, O., Serrão, E.A., Valle, M.   +14 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Effects of pedigree errors on the efficiency of conservation decisions [PDF]

, 2009
Conservation schemes often aim at increasing genetic diversity by minimizing kinship, and the best method to achieve this goal, when pedigree data is available, is to apply optimal contributions.
Bijma, P., Oliehoek, P.A.
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Fragmentation genetics in the tropics [PDF]

, 2018
On the 23rd of February, some 50 Conservation Geneticists from around the global gathered for a half day symposium entitled ‘Fragmentation Genetics in the Tropics' held at the Friedrich-Alexander University, Erlangen, Germany as part of the German ...
Finger, Aline, Kettle, Chris
core  

Development of innovative tools for understanding marine biodiversity and assessing good environmental status: the EU project DEVOTES [PDF]

, 2012
AZTI-Tecnalia organized the XVII edition of SIEBM – Iberian Symposium on Marine Biology Studies, in Donostia – San Sebastián, from 11th to 14th September 2012.
Borja, Àngel
core   +1 more source

Genetics and conservation biology

Comptes Rendus. Biologies, 2003
Conservation genetics encompasses genetic management of small populations, resolution of taxonomic uncertainties and management units, and the use of molecular genetic analyses in forensics and to understanding species' biology. The role of genetic factors in extinctions of wild populations has been controversial, but evidence now shows that they make ...
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source