Results 101 to 110 of about 537,381 (287)
, 2002 We discuss the past and future of set theory, axiom systems and independence results.
A. Blass +10 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Development and validation of an Age-related Language Decline Scale (ALDS) for older adults
Acta PsychologicaObjectives: Language decline in older adults poses a great threat to their independence. A self-report scale designed to measure age-related language decline could be very efficient, but it is still lacking.
Xinan Zhou, Yanping Dong
doaj +1 more source
The cost efficiency of German banks: a comparison of SFA and DEA [PDF]
We investigate the consistency of efficiency scores derived with two competing frontier methods in the financial economics literature: Stochastic Frontier and Data Envelopment Analysis.
Fiorentino, Elisabetta +2 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Hierarchical composite endpoints in clinical trials for multimorbid older adults
EClinicalMedicineSummary: Hierarchical composite endpoints (HCEs) has the potential to make clinical trials for multimorbid older adults more relevant. Unlike conventional time-to-first-event analyses—which can give more weight to outcomes of lesser relevance—HCEs rank ...
Priya Vart
doaj +1 more source
Quality of life among HIV-tuberculosis co-infected patients
Perspectives in Clinical Research, 2019 Background: India is the world's third leading country in terms of people living with human deficiency virus (HIV) (2.1 million) with 0.4 million deaths due to HIV-associated tuberculosis (TB). Physical and mental stress degrades the quality of life (QOL)
Dharmendra Kumar Jha +4 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Evaluation of a solidary academic-pedagogical project in virtual graduate programs
Frontiers in EducationThe consolidation of virtual education as a strategic modality in postgraduate training requires rigorous evaluations of its relevance from the student perspective.
Kris Evelin Ortiz-Ordoñez +2 more
doaj +1 more source