PPAR Research, 2018 Nonalcoholic fatty liver disease or steatohepatitis (NAFLD/NASH) is a fatty liver disease that is closely related to obesity, diabetes, and dyslipidemia. Pioglitazone, which was developed as an antidiabetic drug, is known to improve NALFD.
H. Y. Ahn +5 more
semanticscholar +1 more source
cDNA Cloning of Constitutive Androstane Receptor (CAR) Gene of Japanese Quail [PDF]
, 2007 application/pdfArticledepartmental bulletin ...
74711 +7 more
core
Multiple Routes for Glutamate Receptor Trafficking: Surface Diffusion and Membrane Traffic Cooperate to Bring Receptors to Synapses [PDF]
Science's STKE (electronic resource) : signal transduction
knowledge environment 327 (21/03/2006) 13, 2007 Trafficking of glutamate receptors into and out of synapses is critically involved in the plasticity of excitatory synaptic transmission. Endocytosis and exocytosis of receptors have initially been thought to account alone for this trafficking. However, membrane proteins also traffic through surface lateral diffusion in the plasma membrane. We describe
arxiv
The Critical Role of Carboxy-Terminal Amino Acids in Ligand-Dependent and -Independent Transactivation of the Constitutive Androstane Receptor [PDF]
, 2003 Teemu Andersin +2 more
openalex +1 more source
Activation of Orphan Nuclear Constitutive Androstane Receptor Requires Subnuclear Targeting by Peroxisome Proliferator-activated Receptor γ Coactivator-1α [PDF]
, 2003 Takuma Shiraki +3 more
openalex +1 more source
Unraveling cell-cell communication with NicheNet by inferring active ligands from transcriptomics data [PDF]
arXivLigand-receptor interactions constitute a fundamental mechanism of cell-cell communication and signaling. NicheNet is a well-established computational tool that infers ligand-receptor interactions that potentially regulate gene expression changes in receiver cell populations.
arxiv
Trait-structured chemotaxis: Exploring ligand-receptor dynamics and travelling wave properties in a Keller-Segel model [PDF]
arXivA novel trait-structured Keller-Segel model that explores the dynamics of a migrating cell population guided by chemotaxis in response to an external ligand concentration is derived and analysed. Unlike traditional Keller-Segel models, this framework introduces an explicit representation of ligand-receptor bindings on the cell membrane, where the ...
arxiv
Identification of a Novel Human Constitutive Androstane Receptor (CAR) Agonist and Its Use in the Identification of CAR Target Genes [PDF]
, 2003 Jodi M. Maglich +10 more
openalex +1 more source
Complementary Roles of Farnesoid X Receptor, Pregnane X Receptor, and Constitutive Androstane Receptor in Protection against Bile Acid Toxicity [PDF]
, 2003 Grace L. Guo +7 more
openalex +1 more source
Comparison and Analysis between Human Breast Cancer Cells and Hepatoma Cells for the Effects of Xenobiotic Nuclear Receptors (Constitutive Androstane Receptor, Steroid and Xenobiotic Receptor, and Peroxisome-Proliferator-Activated Receptor γ ) on the Transcriptional Activity of Estrogen Receptor [PDF]
, 2003 openalex +1 more source