Results 191 to 200 of about 69,599 (292)

Hibiscus sabdariffa Extract Protects HaCaT Cells against Phenanthrene-Induced Toxicity through the Regulation of Constitutive Androstane Receptor/Pregnane X Receptor Pathway. [PDF]

Nutrients, 2022
Malar DS, Prasanth MI, Verma K, Prasansuklab A, Tencomnao T.   +4 more
europepmc   +1 more source

The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis [PDF]

, 2006
Yuichi Yamazaki, Satoru Kakizaki, Noriyuki Horiguchi, Naondo Sohara, Ken Sato, Hitoshi Takagi, Masatomo Mori, Masahiko Negishi   +7 more
openalex   +1 more source

Lymphocyte-Specific Protein-1 Suppresses Xenobiotic-Induced Constitutive Androstane Receptor and Subsequent Yes-Associated Protein-Activated Hepatocyte Proliferation. [PDF]

Am J Pathol, 2022
Koral K, Bhushan B, Orr A, Stoops J, Bowen WC, Copeland MA, Locker J, Mars WM, Michalopoulos GK.   +8 more
europepmc   +1 more source

Glucocorticoid Receptor-interacting Protein 1 Mediates Ligand-independent Nuclear Translocation and Activation of Constitutive Androstane Receptor in Vivo

, 2002
Gyesik Min, Jongsook Kim Kemper, Byron Kemper   +2 more
openalex   +1 more source

Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers [PDF]

, 2006
Stephanie Faucette, Tong-Cun Zhang, Rick Moore, Tatsuya Sueyoshi, Curtis J. Omiecinski, Edward L. LeCluyse, Masahiko Negishi, Hongbing Wang   +7 more
openalex   +1 more source

Regulation of Constitutive Androstane Receptor and Its Target Genes by Fasting, cAMP, Hepatocyte Nuclear Factor α, and the Coactivator Peroxisome Proliferator-activated Receptor γ Coactivator-1α [PDF]

, 2006
Xunshan Ding, Kristin Lichti, In‐Sook Kim, Frank J. Gonzalez, Jeff L. Staudinger   +4 more
openalex   +1 more source

Activation of PXR, CAR and PPARα by pyrethroid pesticides and the effect of metabolism by rat liver microsomes

Heliyon, 2019
In this study, we used reporter gene assays in COS-1 cells to examine the activation of rat pregnane X receptor (PXR), rat constitutive androstane receptor (CAR) and rat peroxisome-proliferator activated receptor (PPAR)α by pyrethroid pesticides, and to ...
Chieri Fujino, Yoko Watanabe, Seigo Sanoh, Hiroyuki Nakajima, Naoto Uramaru, Hiroyuki Kojima, Kouichi Yoshinari, Shigeru Ohta, Shigeyuki Kitamura   +8 more
doaj  

Constitutive Androstane Receptor (CAR) as a Potential Sensing Biomarker of Persistent Organic Pollutants (POPs) in Aquatic Mammal: Molecular Characterization, Expression Level, and Ligand Profiling in Baikal Seal (Pusa sibirica) [PDF]

, 2006
Hiroki Sakai, Hisato Iwata, Eun‐Young Kim, Oyuna Tsydenova, Nobuyuki Miyazaki, Е. А. Петров, Valeriy Batoev, Shinsuke Tanabe   +7 more
openalex   +1 more source

Cross-species comparison of CAR-mediated procarcinogenic key events in a 3D liver microtissue model [PDF]

, 2019
Ball, Graeme, Beaumont, Bobby, Cowie, David, Currie, Richard, McInnes, Liz, Peffer, Rich, Plummer, Simon, Wallace, Stephanie, Wright, Jayne   +8 more
core   +2 more sources

Nuclear Receptor Coactivator 6 Mediates the Synergistic Activation of Human Cytochrome P-450 2C9 by the Constitutive Androstane Receptor and Hepatic Nuclear Factor-4α [PDF]

, 2008
Sailesh Surapureddi, Ritu Rana, Janardan K. Reddy, Joyce A. Goldstein   +3 more
openalex   +1 more source