Results 91 to 100 of about 736,297 (294)

NEML2: An efficient and modular multiphysics constitutive modeling library for hybrid computing environments

SoftwareX
This paper presents NEML2, an open-source, high-performance library developed for constitutive material modeling, designed to support the flexible and modular development of models for complex material behavior.
Tianchen Hu, Mark C. Messner
doaj   +1 more source

Extended concept of representative directions to describe inelastic behaviour of electrospun polymers [PDF]

, 2019
The concept of representative directions allows one to generalize onedimensional uniaxial material models to more general constitutive equations, suitable for arbitrary multi-axial loading scenarios.
Shutov, Alexey V.
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

A constitutive model for an overlay coating [PDF]

Coatings are frequently applied to gas turbine blades and vanes to provide protection against oxidation and corrosion. The results of an experimental and analytical study to develop a constitutive model for an overlay coating is presented. Specimens were
Nissley, D. M., Swanson, G. A.
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Comparison of phenomenological and physical-based constitutive material models for Cr17Mn17Mo3NiN low nickel stainless steel

Materials Research Express
Phenomenological and physical-based constitutive models for the Cr17Mn17Mo3NiN low nickel stainless steel were developed based on the true stress–strain curves acquired from isothermal uniaxial compression tests.
Gun Song Jang, Kyong Ho Sim
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Mechanical constitutive model of stand off damping composites layered rubber core under wide strain rates

Scientific Reports
To characterize the dynamic mechanical response and vibration-damping characteristics of a layered rubber core (LRC) in a stand-off damping structure, a series of experiments were carried out and a continuous power-law variable fractional-order Kelvin ...
Zhangda Zhao, Wenjun Meng, Bijuan Yan, Guansen Qiao, Yuan Qin, Yao Wang, Tao Yang, Hong Ren   +7 more
doaj   +1 more source

Ballistic Performance of Thermoplastic Fiber-Reinforced Metal Laminates Subjected to Impact Loadings

Applied Sciences
This paper aims to predict the damage and fracture behavior of thermoplastic fiber-reinforced metal laminates (TFMLs) under ballistic impact loadings.
Yan Zeng, Chunguang Li, Hong Zheng, Yijun Liu   +3 more
doaj   +1 more source

A unified creep-plasticity model suitable for thermo-mechanical loading [PDF]

An experimentally based unified creep-plasticity constitutive model was implemented for 1070 steel. Accurate rate and temperature effects were obtained for isothermal and thermo-mechanical loading by incorporating deformation mechanisms into the ...
Sehitoglu, H., Slavik, D.
core   +1 more source