Results 51 to 60 of about 50,089 (313)
POOC- a platform for object-oriented constraint programming
, 2022 S.159-170In this paper, we describe an implementation-independent object-oriented interface for commercial and academic Constraint Solvers. This serves as a basis for evaluating different Constraint Solvers and for developing solver-independent ...
Schlenker, H., Ringwelski, G.
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
CONSTRAINT PROGRAMMING AND UNIVERSITY TIMETABLING
South African Journal of Industrial Engineering, 2012 <p>ENGLISH ABSTRACT: The technology of Constraint Programming is rapidly becoming a popular alternative for solving large-scale industry problems.
G.W. Groves, W. Van Wijck
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Surgical Operation Scheduling with Goal Programming and Constraint Programming: A Case Study
Mathematics, 2019 The achievement of health organizations’ goals is critically important for profitability. For this purpose, their resources, materials, and equipment should be efficiently used in the services they provide.
Şeyda Gür +2 more
doaj +1 more source
A system for SMT based constraint programming in Java
, 2017 This paper presents a system for constraint programming in Java using translation of JVM bytecode into SMT. This allows the constraints to be written in normal Java, to being interoperable with the rest of the program and lowers the entry barrier to ...
Funk, Maurice
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Combining Constraint Programming Reasoning with Large Language Model Predictions [PDF]
Constraint Programming (CP) and Machine Learning (ML) face challenges in text generation due to CP's struggle with implementing "meaning" and ML's difficulty with structural constraints.
De Maria, Elisabetta +2 more
core +2 more sources
A Hybrid Method for the Modelling and Optimisation of Constrained Search Problems
Foundations of Management, 2014 The paper presents a concept and the outline of the implementation of a hybrid approach to modelling and solving constrained problems. Two environments of mathematical programming (in particular, integer programming) and declarative programming (in ...
Sitek Pawel, Wikarek Jaroslaw
doaj +1 more source
Mathematical Modelling and Analysis, 2015 This paper illustrates a procedure to generate pareto optimal solutions of multi-objective linear fractional programming problem (MOLFPP) with closed interval coefficients of decision variables both in objective and constraint functions.
Suvasis Nayak, Akshay Ojha
doaj +1 more source