Results 61 to 70 of about 21,873 (292)
Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. [PDF]
, 2016 Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states.
Guan, Zhonghui +2 more
core +2 more sources
Advanced Functional Materials, EarlyView.The pH‐sensitive His6‐SWNTs, which is functionalized with oligohistidine, can deliver STTM396 molecules into callus cells. The STTM396–SWNT complex treatments enhance shoot regeneration efficiency by regulating the miR396‐GRF module in Arabidopsis and tomato calli.
Yeong Yeop Jeong +7 more
wiley +1 more source
Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2 [PDF]
, 2015 Rationale: Chronic elevation of 3'-5'-cyclic adenosine monophosphate (cAMP) levels has been associated with cardiac remodelling and cardiac hypertrophy.
Aronsen, Jan M. +24 more
core +1 more source
Biosupercapacitors for Human‐Powered Electronics
Advanced Functional Materials, EarlyView.Biosupercapacitors are emerging as biocompatible and integrative energy systems for next‐generation bioelectronics, offering rapid charge–discharge performance and mechanical adaptability. This review systematically categorizes their applications from external to organ‐level systems and highlights their multifunctional roles in sensing, actuation, and ...
Suhyeon Kim +7 more
wiley +1 more source
Novel pathways of heart failure with preserved ejection fraction [PDF]
, 2016 INTRODUCTION: Diastolic heart failure (HF) i.e., HF with preserved ejection fraction (HFpEF) accounts for ~50% of all clinical HF presentations; but unlike systolic HF i.e., HF with reduced ejection fraction (HFrEF), there are no evidenced based ...
Li, Shanpeng
core +2 more sources
MicroRNA-1 downregulation increases connexin 43 displacement and induces ventricular tachyarrhythmias in rodent hypertrophic hearts. [PDF]
PLoS ONE, 2013 Downregulation of the muscle-specific microRNA-1 (miR-1) mediates the induction of pathologic cardiac hypertrophy. Dysfunction of the gap junction protein connexin 43 (Cx43), an established miR-1 target, during cardiac hypertrophy leads to ventricular ...
Antonio Curcio +14 more
doaj +1 more source
PATHOLOGICAL EVALUATION OF DORSAL ROOT GANGLIA AND SPINAL CORD AND SCIATIC NERVE FOLLOWING A CHRONIC CONSTRICTION INJURY OF THE SCIATIC NERVE IN RATS [PDF]
Kafrelsheikh Veterinary Medical Journal, 2019 Objective: To study pathological changes on spinal cord and dorsal root ganglia (DRG) and sciatic nerve itself after sciatic nerve injury in rats Design: Randomized experimental study Procedure: Rats were randomly divided into two main groups. Control group (25 rats) without any treatment and treated group (n=50) with induced chronic constriction ...
Al-Shimaa E Elsayed +3 more
openaire +1 more source
Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME
Advanced Functional Materials, EarlyView.A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li +10 more
wiley +1 more source
Jornal Brasileiro de Pneumologia, 2007 A estenose idiopática de traquéia é incomum. Relatam-se quatro casos com quadro clínico semelhante: história de tratamento de broncoespasmo sem resultado e diagnóstico por broncoscopia. O tratamento em três pacientes foi dilatação e corticóide sistêmico;
Carolina Rossi +4 more
doaj +1 more source
Diagnostic and Therapeutic Approach in Intestinal Tuberculosis [PDF]
, 2016 Tuberculosis was still a global health problem. Beside lung, tuberculosis also manifest in other organs, one among them is in abdominal organs. Abdominal tuberculosis was a complex disease with unspecific sign and symptoms so that its diagnostic ...
Guno, T. H. (Tri) +3 more
core +1 more source