Results 111 to 120 of about 2,621 (293)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Constructal Design of Elliptical Cylinders with Heat Generating for Entropy Generation Minimization. [PDF]

Entropy (Basel), 2020
Wang R, Xie Z, Yin Y, Chen L.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Flow Evolution in Magmatic Conduits: A Constructal Law Analysis of Stochastic Basaltic and Felsic Lava Dynamics

Fluids
This study probabilistically assesses magma ascent by modeling dike propagation as a fully coupled fluid-flow, thermo-mechanical problem, explicitly accounting for the stochastic heterogeneity of the crustal host rock.
Antonio F. Miguel, Vinícius R. Pepe, Luiz A. O. Rocha   +2 more
doaj   +1 more source

Constructal Design of an Arrow-Shaped High Thermal Conductivity Channel in a Square Heat Generation Body. [PDF]

Entropy (Basel), 2020
Zhang F, Feng H, Chen L, You J, Xie Z.
europepmc   +1 more source

An assessment of branching asymmetry of the tracheobronchial tree. [PDF]

Sci Rep, 2022
Miguel AF.
europepmc   +1 more source

Mathematical model of a constructal Coanda effect nozzle [PDF]

, 2016
This paper analyses the ACHEON Coanda effect nozzle for aircraft propulsion, based on the dynamic equilibrium of two jet streams. The ACHEON concept, and, in particular, the HOMER nozzle, which is its main component, are presented, together with the ...
Angeli, Diego, Maharshi, Subhash, Stewart, Jill, Trancossi, Michele   +3 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Constructal Optimization of Rectangular Microchannel Heat Sink with Porous Medium for Entropy Generation Minimization. [PDF]

Entropy (Basel), 2021
Li W, Xie Z, Xi K, Xia S, Ge Y.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source