Results 61 to 70 of about 2,587 (272)
Constructal theory of pattern formation [PDF]
Hydrology and Earth System Sciences, 2007 This review article shows that the occurrence of macroscopic flow configuration is a universal natural phenomenon that can be explained and predicted on the basis of a principle of physics (the constructal law): "For a flow system to persist in time
A. Bejan
doaj
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Structure and adaptation of arteries to pulsatile flow - The case of the ascending aorta [PDF]
, 2014 PURPOSE: The objectives are: (i) assess the development of the impedance of some arteries during the first decades of life; (ii) determine the influence of pulse rate in arterial impedance; (iii) compare the structure of some arterial segments with ...
Silva, Carla
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Constructal vascularized structures
Open Engineering, 2015 Smart features such as self-healing and selfcooling require bathing the entire volume with a coolant or/and healing agent. Bathing the entire volume is an example of point to area (or volume) flows.
Cetkin Erdal
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
O aparecimento da forma e estrutura em sistemas naturais e fabricados: a visão da teoria constructal [PDF]
, 2007 Porque é que a forma e a estrutura são uma característica dos sistemas de escoamento? Como é que aparecem? O que é que há de comum entre sistemas tão distintos como as bacias hidrográficas, o sistema respiratório, as colónias de bactérias ou corais, a ...
Miguel, A. F.
core
Constructive Methods of Program Design [PDF]
, 1976 Correct programs cannot be obtained by attempts to test or to prove incorrect programs: the correctness of a program should be assured by the design procedure used to build it.
openaire +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Mathematical model of a constructal Coanda effect nozzle [PDF]
, 2016 This paper analyses the ACHEON Coanda effect nozzle for aircraft propulsion, based on the dynamic equilibrium of two jet streams. The ACHEON concept, and, in particular, the HOMER nozzle, which is its main component, are presented, together with the ...
Angeli, Diego +3 more
core +1 more source