Results 81 to 90 of about 9,281,684 (290)
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Perspective: the gist of public tender for service design [PDF]
Governments around the world are increasingly formalising design as an innovative approach to renew public services. In this development, the capabilities of external service design consultancies often play an important part, which calls for new insights
Person, Oscar +3 more
core +1 more source
Este estudo numérico utiliza o método Constructal Design para reduzir os pontos quentes de um sistema com geração de calor uniforme por unidade de volume através da transferência de calor por condução.
Cássia Cris Beckel +3 more
doaj +4 more sources
Constructal design for a clover-shaped high conductivity channel in a square heat generating body
Constructal design of a square heat generating body with a clover-shaped high thermal conductivity channel is carried out. The research focuses on minimizing the maximum temperature difference and the entropy generation rate by releasing degrees of ...
Lingen Chen +4 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Constructal allocation of nanoparticles in nanofluids
We perform a constructal design of heat conduction in a blade-configured disk-shaped domain with uniform heat generation and periphery heat-sink by introducing a transition line from two-path conduction to one-path conduction in the domain.
Bai, C, Wang, L
core +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Constructal design of I and T-shaped channels used in a resin infusion process
The resin infusion is a manufacturing technology usually applied to produce structures made of composite materials widely employed in automotive, marine and aerospace industries.
dos Santos, Elizaldo Domingues +7 more
core
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source

