Results 71 to 80 of about 9,281,684 (290)
Introducing Experience Goals into Packaging Design [PDF]
, 2016 Consumer experiences are an increasingly important driving force for commerce, affecting also packaging design. Yet, experience design for packages is rarely studied.
Roto, Virpi +3 more
core +1 more source
Construction of Designs on the 2-Sphere
European Journal of Combinatorics, 1991 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Design and Construction of “Synthetic Species”
PLoS ONE, 2012 Synthetic biology is an area of biological research that combines science and engineering. Here, I merge the principles of synthetic biology and regulatory evolution to create a new species with a minimal set of known elements. Using preexisting transgenes and recessive mutations of Drosophila melanogaster, a transgenic population arises with small ...
openaire +6 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The Constructal Law and the Design of the Biosphere: Nature and Globalization
, 2010 “Design in nature” is a topic of growing interest throughout science. The constructal law is the physics law of design generation and evolution in nature: “for a flow system to persist in time (to live), it must evolve such that it provides easier and ...
Sylvie Lorente, Adrian Bejan
core +1 more source
Constructions of Spherical 3-Designs
Graphs and Combinatorics, 1998 Spherical t-designs are Chebyshev-type averaging sets on the d-sphere S^d which are exact for polynomials of degree at most t. This concept was introduced in 1977 by Delsarte, Goethals, and Seidel, who also found the minimum possible size of such designs, in particular, that the number of points in a 3-design on S^d must be at least n>=2d+2. In this
openaire +4 more sources
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Tree-Shaped Flow Structures Viewed from the Constructal Theory Perspective
, 2012 Constructal theory, conceived by Adrian Bejan, is the view that the generation of configuration in nature is a universal phenomenon, which is covered by a law of physics-the constructal law.
Miguel, A. F.
core +1 more source