Results 91 to 100 of about 1,839 (290)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Branching in fluidic networks with permeable walls: an extension of Hess-Murray’s law [PDF]
, 2017 The branching of fluidic networks becomes a subject of great interest due to its importance in understanding the behavior of branching networks in biology (cardiovascular and bronchial systems, river basins, the structure of plants and trees, etc..), as ...
Miguel, A. F. +2 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Rethinking evolution, entropy and economics: A triadic conceptual framework for the maximum entropy principle as applied to the growth of knowledge [PDF]
Recently, the maximum entropy principle has been applied to explain the evolution of complex non-equilibrium systems, such as the Earth system. I argue that it can also be fruitfully deployed to reconsider the classical treatment of entropy in economics ...
Herrmann-Pillath, Carsten
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Constant depth microfluidic networks based on a generalised Murray’s law for Newtonian and power-law fluids [PDF]
, 2014 This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014) +4 more
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Constructive Quantum Field Theory
, 2006 A review of the renormalization group approach to the proof of non perturbative ultraviolet stability in scalar field theories in dimension d=2,3.
openaire +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
OPTIMIZATION OF CONTAINER TERMINAL FLOWS THROUGH A CONSTRUCTAL APPROACH AND FLUID FLOW ANALOGY
Journal of Industrial Design and Engineering Graphics, 2014 The existing movement for the reduction of environmental impact and improvement of efficiency of processes led to a need for optimizing the transport and logistic chains.
OANCEA Laurentiu
doaj
A Critical Reassessment of the Hess–Murray Law
Entropy, 2016 The Hess–Murray law is a correlation between the radii of successive branchings in bi/trifurcated vessels in biological tissues. First proposed by the Swiss physiologist and Nobel laureate Walter Rudolf Hess in his 1914 doctoral thesis and published in ...
Enrico Sciubba
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source