Results 111 to 120 of about 8,837,157 (332)
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Thermodynamics 2.0: Bridging the natural and social sciences. [PDF]
Philos Trans A Math Phys Eng Sci, 2023 Poudel R +5 more
europepmc +1 more source
Applied SciencesThe continuous increase in electronic power densities demands thermal management solutions that surpass the conventional heat sink designs. This study introduces a synergistic approach that combines constructal design principles with Friction Stir ...
Joel de Jesus +2 more
doaj +1 more source
Rethinking evolution, entropy and economics: A triadic conceptual framework for the maximum entropy principle as applied to the growth of knowledge [PDF]
, 2010 Recently, the maximum entropy principle has been applied to explain the evolution of complex non-equilibrium systems, such as the Earth system. I argue that it can also be fruitfully deployed to reconsider the classical treatment of entropy in economics ...
Herrmann-Pillath, Carsten
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Natural Fractals as Irreversible Disorder: Entropy Approach from Cracks in the Semi Brittle-Ductile Lithosphere and Generalization. [PDF]
Entropy (Basel), 2022 Venegas-Aravena P, Cordaro EG, Laroze D.
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Engineering Flow and Design [PDF]
, 2015 The importance of design in natural and engineered flow systems is undisputed. It is not only essential to life, but also plays a crucial role in our technological world.
Miguel, A. F. +2 more
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Simultaneous Extrema in the Entropy Production for Steady-State Fluid Flow in Parallel Pipes
, 2010 Steady-state flow of an incompressible fluid in parallel pipes can simultaneously satisfy two contradictory extremum principles in the entropy production, depending on the flow conditions.
Andresen +37 more
core +1 more source