Results 61 to 70 of about 5,380,639 (293)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Constructal theory of pattern formation [PDF]
, 2006 International audienceThis review article shows that the occurrence of macroscopic flow configuration is a universal natural phenomenon that can be explained and predicted on the basis of a principle of physics (the constructal law): "For a flow system ...
Bejan, A.
core +2 more sources
Indigenous Concepts of ‘Living Systems’: Aristotelian ‘Soul’ meets Constructal Theory
Ethnobiology Letters, 2015 I examine similarities among the ways of thinking concerning the natural world of Indigenous peoples of North America and Australia and two aspects of Western Science from different historical periods.
Raymond Pierotti
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Constructal Theory: a new approach to spatial economics and finance [PDF]
, 2009 This paper illustrates an application of Constructal Theory to spatial economics and Þnance. Constructal theory is about the generation of architecture in ßow systems in general.
Heitor Reis, António +1 more
core
Vascular structures for smart features self-cooling and self-healing
Journal of Thermal Engineering, 2017 Here we show how smart features of self-cooling and self-healing can be gained to mechanical systems with embedded vascular structures. Vascular structures mimic the circulatory system of animals.
E. Cetkin
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Constructal law & thermoeconomics
, 2016 In spite of evident differences, Constructal Theory and Thermoeconomics (in particular thermoeconomic optimization) have also some similarities. For instance, they both suggest the optimal allocation of two different types of losses: high permeability vs.
Mauro Reini, REINI, MAURO
core +1 more source
Constructal design of T-shaped cavity cooled by convection
, 2011 In this paper, we rely on the Constructal method to optimize the geometry of a T-shaped cavity intruded into a conducting solid wall. The cavity is cooled by a steady stream of convection while the solid generates heat uniformly and it is insulated on ...
Dos Santos E. D. +10 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source