Results 71 to 80 of about 1,839 (290)
Optimal branching structure of fluidic networks with permeable walls [PDF]
, 2017 Biological and engineering studies of Hess-Murray’s law are focused on assemblies of tubes with impermeable walls. Blood vessels and airways have permeable walls to allow the exchange of fluid and other dissolved substances with tissues.
Miguel, A. F., Pepe, V. R., Rocha, L.A.O
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
O aparecimento da forma e estrutura em sistemas naturais e fabricados: a visão da teoria constructal [PDF]
, 2007 Porque é que a forma e a estrutura são uma característica dos sistemas de escoamento? Como é que aparecem? O que é que há de comum entre sistemas tão distintos como as bacias hidrográficas, o sistema respiratório, as colónias de bactérias ou corais, a ...
Miguel, A. F.
core
Climate change, in the framework of the constructal law [PDF]
, 2011 Here we present a simple and transparent alternative to the complex models of Earth thermal behavior under time-changing conditions. We show the one-to-one relationship between changes in atmospheric properties and time-dependent changes in temperature ...
Alberton, Bruna +5 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Design and Optimization of Thermophotovoltaic System Cavity with Mirrors
Energies, 2016 Thermophotovoltaic (TPV) systems can convert radiant energy into electrical power. Here we explore the design of the TPV system cavity, which houses the emitter and the photovoltaic (PV) cells. Mirrors are utilized in the cavity to modify the spatial and
Tian Zhou +4 more
doaj +1 more source
“Recent Advances in Energy Research” [PDF]
, 2008 The worldwide scarcity of fossil fuels regarding primary energy demand together with growing environmental concerns have raised new challenges to the world economy, and led to changes in the energy paradigm.
Miguel, A. F., Reis, A. Heitor
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Thermal Optimization of an Array of Needle-Shaped using Constructal Theory [PDF]
International Journal of Advanced Design and Manufacturing Technology, 2018 In the present paper, the constructal theory is employed to determine the optimal configuration of three rows of needle-shaped fins. The heat transfer across the fins is due to laminar forced convection.
Maryam Hoseinzadeh +2 more
doaj