Results 71 to 80 of about 8,837,157 (332)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Alexandria Engineering Journal, 2022 This study presented a novel liquid-cooled heat sink based on constructal theory. An experiment was conducted to investigate the influence of boundary conditions, such as the mass flow rate (ṁ), on heat transfer rate (Qin) and pressure drop.
Kittipong Sakamatapan +6 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
, 2014 Bejan's Constructal theory has provided a dramatic contribution to the design of natural and industrial systems, mainly because all sort of flows tend to follow precise rules which Bejan was able to explain.
G. Lorenzini, S. Moretti
semanticscholar +1 more source
O aparecimento da forma e estrutura em sistemas naturais e fabricados: a visão da teoria constructal [PDF]
, 2007 Porque é que a forma e a estrutura são uma característica dos sistemas de escoamento? Como é que aparecem? O que é que há de comum entre sistemas tão distintos como as bacias hidrográficas, o sistema respiratório, as colónias de bactérias ou corais, a ...
Miguel, A. F.
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Design and Optimization of Thermophotovoltaic System Cavity with Mirrors
Energies, 2016 Thermophotovoltaic (TPV) systems can convert radiant energy into electrical power. Here we explore the design of the TPV system cavity, which houses the emitter and the photovoltaic (PV) cells. Mirrors are utilized in the cavity to modify the spatial and
Tian Zhou +4 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Thermal Optimization of an Array of Needle-Shaped using Constructal Theory [PDF]
International Journal of Advanced Design and Manufacturing Technology, 2018 In the present paper, the constructal theory is employed to determine the optimal configuration of three rows of needle-shaped fins. The heat transfer across the fins is due to laminar forced convection.
Maryam Hoseinzadeh +2 more
doaj