Results 111 to 120 of about 2,425,065 (336)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

The Flame-Retardant Mechanisms and Preparation of Polymer Composites and Their Potential Application in Construction Engineering. [PDF]

Polymers (Basel), 2021
Shen J, Liang J, Lin X, Lin H, Yu J, Wang S.   +5 more
europepmc   +1 more source

Engineering, construction, and operations in space [PDF]

The century-old Mond process for carbonyl extraction of metals from ore shows great promise as an efficient low energy scheme for producing high-purity Fe, Ni, Cr, Mn, and Co from lunar or asteroidal feedstocks.
Johnson, Stewart W., Wetzel, John P.
core   +1 more source

Innovation in construction eBusiness [PDF]

, 2011
The use of e-Business within the construction industry has steadily grown over the last decade. However, despite the successes being widely publicized, it is perceived that progress is limited and constrained within the industry.
Ingirige, MJB, Perera, SC, Ruikar, K
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Research on a Carbon Emission Prediction Model for the Construction Phase of Underground Space Engineering Based on Typical Resource Carbon Consumption and Its Application

Buildings
The trend of global warming remains severe. As one of the major sources of carbon emissions, the construction industry still requires large-scale and effective transformations.
Yuan Mei, Haokun Wang, Dongbo Zhou
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Leveraging digital tools to advance mathematics competencies among construction students

Cogent Education
This study investigated the impact of integrating design-technological activities on developing mathematical competencies among construction engineering students. A mixed methods approach compared curriculum delivery with and without digital tools across
Elmira Saparbayeva, Marzhan Abdualiyeva, Yerlan Torebek, Nurlibay Madiyarov, Abay Tursynbayev   +4 more
doaj   +1 more source

Early intervention mechanism for preventing electrocution in construction engineering. [PDF]

Ind Health, 2021
Shiau YR, Lo FY, Ko PC.
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source