Results 201 to 210 of about 3,656 (265)

Sodium Ascorbate‐Accelerated Gelling Hydrogels With Rapid Self‐Mineralized Capacity for Chronic Wounds

open access: yesAdvanced Science, EarlyView.
An immunoregulatory hydrogel based on sodium ascorbate (SA)‐accelerated gelation and in situ self‐mineralization is prepared here. Such a hydrogel is constructed by mixing benzaldehyde‐ and cyanoacetate‐functionalized dextran with silver nitrate (AgNO3) and SA, enabling the ultrafast solidification and in situ self‐mineralization of silver ...
Xiaoya Ding   +4 more
wiley   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun   +10 more
wiley   +1 more source

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

open access: yesAdvanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li   +7 more
wiley   +1 more source

Supercritical CO2‐Induced Porous MXene Films for Electromagnetic Interference Shielding and Infrared Stealth

open access: yesAdvanced Science, EarlyView.
The phase transition of supercritical CO2 induces the foaming of dense MXene film without compromise inherent structure of MXene nanosheet. The foamed porous MXene film manifests remarkable EMI shielding and infrared thermal camouflage performances. Moreover, the foaming strategy is broadly adaptable and can be extended to other two‐dimensional films ...
Hui Zhao   +7 more
wiley   +1 more source

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