Results 41 to 50 of about 3,458,657 (253)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Can (dynamic) social norms encourage plant-based food purchases? a quasi-experimental study in real-world Dutch supermarkets

BMC Medicine
Background Communicating (dynamic) social norms is considered a promising tool to stimulate healthy and sustainable food choices. The aim of the present study was to evaluate to what extent a (dynamic) social norm intervention in real-world supermarkets ...
Sofia M. M. Wolfswinkel, Sanne Raghoebar, Josine M. Stuber, Emely de Vet, Maartje P. Poelman   +4 more
doaj   +1 more source

Alternative method’s results for the non targeted determination of xenobiotics in food by means of high resolution and accuracy mass spectrometry

International Journal of Food Contamination, 2021
The application of a high resolution and accurate mass spectrometry (HRAMS) approach to detect xenobiotics in different food matrices by means of non targeted determination by UHPLC-Orbitrap followed by data processing analysis was described.
Rossana Scarpone, Rachele Rocchi, Federico Bacà, Roberta Rosato, Francesco Chiumiento, Giacomo Migliorati   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Temptation at every corner: exploring public perceptions of food cues and policy support for governmental food cue regulation in outdoor public spaces

BMC Medicine
Background Unhealthy visual food cues in outdoor public spaces are external drivers of unhealthy diets. Food cues are visible situations associated with food-related memories.
Tamika M. Wopereis, Sanne K. Djojosoeparto, Frédérique C. Rongen, Sanne C. Peeters, Emely de Vet, Maartje P. Poelman   +5 more
doaj   +1 more source

Multicriteria approach for evaluating biowaste-valorization cases

Energy Storage and Saving
The selection of waste-valorization projects is a complex decision process that involves many factors and variables to guarantee an appropriate definition of the best waste-management strategy to be applied for a specific waste typology.
Carlota Díaz García, Maryori Díaz, Elena Laborda, María Pérez, Pantelis Pekakis   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Determinants, behaviour change techniques and pedagogical approaches used in secondary school-based food and nutrition programmes: a qualitative study of the SWITCH project

BMC Public Health
Background Food and nutrition programmes at secondary schools have the potential to improve public and planetary health, as they target a wide range of adolescents.
Anouk Mesch, Madelief Engels, Sanne Raghoebar, Laura H. H. Winkens, Judith Gulikers, Renate Wesselink, Annemien Haveman-Nies   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The food environment through the eyes of adolescents: exploring socioecological factors and opportunities for healthy and sustainable food choices

BMC Public Health
Background Although it is evident that current food environments do not facilitate healthy and sustainable diets, it is still largely unknown how adolescents navigate their food environments during the school week. This study explored how adolescents, in
Anouk Mesch, Femke Hoefnagels, Judith Gulikers, Renate Wesselink, Laura H.H. Winkens, Sanne Raghoebar, Annemien Haveman-Nies   +6 more
doaj   +1 more source