Results 51 to 60 of about 1,302,805 (312)

Binding Direction-Based Two-Dimensional Flattened Contact Area Computing Algorithm for Protein–Protein Interactions

open access: yesMolecules, 2017
Interactions between protein molecules are essential for the assembly, function, and regulation of proteins. The contact region between two protein molecules in a protein complex is usually complementary in shape for both molecules and the area of the ...
Beom Sik Kang   +2 more
doaj   +1 more source

Contact mechanics with adhesion: Interfacial separation and contact area [PDF]

open access: yesEPL (Europhysics Letters), 2008
We study the adhesive contact between elastic solids with randomly rough, self affine fractal surfaces. We present molecular dynamics (MD) simulation results for the interfacial stress distribution and the wall-wall separation. We compare the MD results for the relative contact area and the average interfacial separation, with the prediction of the ...
Yang, C.   +3 more
openaire   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

How do we get people into contact? Predictors of intergroup contact and drivers of contact seeking [PDF]

open access: yes, 2020
Compared to the impressive amount of research on consequences of intergroup contact, relatively little work has been devoted to predictors of intergroup contact.
Beneda, Marta   +36 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

MD simulation of the effect of contact area and tip radius on nanoindentation

open access: yes, 2004
Molecular dynamics simulations of nanoindentation are performed on monocrystal copper. A new "contact atoms" method is presented for calculating the contact area.
Chen SD   +2 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Tire-Pavement Friction Characteristics with Elastic Properties of Asphalt Pavements

open access: yesApplied Sciences, 2017
The skid-resisting performance of pavement is a critical factor in traffic safety. Recent studies primarily analyze this behavior by examining the macro or micro texture of the pavement.
Miao Yu   +3 more
doaj   +1 more source

On the Proportionality Between Area and Load in Line Contacts [PDF]

open access: yesTribology Letters, 2018
The relative contact area of rough surface contacts is known to increase linearly with reduced pressure, with proportionality factor κ . In its common definition, the reduced pressure contains the root-mean-square gradient (RMSG) of the surface. Although easy to measure, the RMSG of the entire surface does not coincide, at small loads, with the RMSG ...
van Dokkum, J.S. (author)   +3 more
openaire   +4 more sources

Effect on oxides on surface topography and thermal contact resistance [PDF]

open access: yes, 1979
The effect of oxides on the topographies of various random engineering surfaces and steady-state thermal contact resistances between oxidefree and oxidized metallic surfaces in contact in high vacua have been investigated. The results of many previous
Mian, M. N.
core  

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