Results 61 to 70 of about 8,751,318 (290)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Laporan Oktober 2018 Perpustakaan Universitas Medan Area

open access: yes, 2018
43 HalamanPuji syukur kepada Allah SWT, karena atas Karunia dan Rahmat-Nya laporan bulanan Perpustakaan Universitas Medan Area Bulan Oktober 2018 dapat tersusun dengan baik.
Perpustakaan, Universitas Medan Area
core   +1 more source

Laporan Maret 2019 Perpustakaan Universitas Medan Area

open access: yes, 2019
73 HalamanPuji syukur kepada Allah SWT, karena atas Karunia dan Rahmat-Nya laporan bulanan Perpustakaan Universitas Medan Area Bulan Maret 2019 dapat tersusun dengan baik.
Perpustakaan, Universitas Medan Area
core   +1 more source

Laporan Mei 2019 Perpustakaan Universitas Medan Area

open access: yes, 2019
66 HalamanPuji syukur kepada Allah SWT, karena atas Karunia dan Rahmat-Nya laporan bulanan Perpustakaan Universitas Medan Area Bulan Mei 2019 dapat tersusun dengan baik.
Perpustakaan, Universitas Medan Area
core   +1 more source

Cohesive Crack with Partially Contacting Faces in Section of the Road Covering

open access: yesМеханика машин, механизмов и материалов, 2012
The case of a longitudinal crack with interfacial bonds in section of a road covering with partially contacting faces is considered. It is considered, that under action of external loading (cave-in of a wheel in a rough surface of a covering) in a zone ...
Sh.G. Hasanov
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

On the Proportionality Between Area and Load in Line Contacts [PDF]

open access: yesTribology Letters, 2018
The relative contact area of rough surface contacts is known to increase linearly with reduced pressure, with proportionality factor κ . In its common definition, the reduced pressure contains the root-mean-square gradient (RMSG) of the surface. Although easy to measure, the RMSG of the entire surface does not coincide, at small loads, with the RMSG ...
van Dokkum, J.S. (author)   +3 more
openaire   +4 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Dynamic Behaviors of Contact Surfaces in the Sliding Friction of a Soft Material

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2007
It is known that detachment waves are generated on the surface of a soft material when it is slid on a hard surface under certain conditions. In the present study, the variation in the contact area that arises when a plate of a cross-linked polymer, poly-
Satoru MAEGAWA, Ken NAKANO
doaj   +1 more source

Williamsburg Area Bicyclists Records

open access: yes, 2006
Primarily issues of the newsletter of the Williamsburg Area Bicyclists, "The Flying Wheel," dated from July 2006 to May 2007. There is also artwork, recurring advertisements, and information on the production of the newsletter.
Williamsburg Area Bicyclists
core  

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