Results 41 to 50 of about 432,503 (265)

Contact-force monitoring increases accuracy of right ventricular voltage mapping avoiding “false scar” detection in patients with no evidence of structural heart disease

open access: yesIndian Pacing and Electrophysiology Journal, 2020
Purpose: Electroanatomical mapping (EAM) could increase cardiac magnetic resonance imaging (CMR) sensitivity in detecting ventricular scar. Possible bias may be scar over-estimation due to inadequate tissue contact.
Luigi Sciarra   +15 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Sliding Mode Contact Force Control of n-Dof Robotics by Force Estimation

open access: yesMajlesi Journal of Electrical Engineering
Control of the force exerted on an object is important for boosting system performance in robotics manipulators. Any undesired applied force may leave remarkable effects on the system, with the potential to damage the object.
Majid Namnabat   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Identification Algorithm of Rail Transit Pantograph-catenary Contact Force Abnormality Based on LSTM Prediction Error

open access: yesChengshi guidao jiaotong yanjiu
Objective Contact force is a crucial aspect of comprehensive detection in the rail transit PC (pantograph-catenary) system and serves as an important evaluation factor of PC system performance.
YANG Jinsong   +5 more
doaj   +1 more source

Effect of Pebble Size Distribution and Wall Effect on Inner Packing Structure and Contact Force Distribution in Tritium Breeder Pebble Bed

open access: yesEnergies, 2021
In the tritium breeding blanket of nuclear fusion reactors, the heat transfer behavior and thermal-mechanical response of the tritium breeder pebble bed are affected by the inner packing structure, which is crucial for the design and optimization of a ...
Baoping Gong   +5 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Identification of force chains in wet coal dust layer and the effect of porosity on three-body contact stiffness

open access: yesScientific Reports
Aiming at the three-body contact problem of mechanical rough surface containing wet coal dust interface, the three-body contact model of rough surface containing wet coal dust interface is constructed by comprehensively considering the contact ...
Xinwei Yang   +4 more
doaj   +1 more source

Dynamic Characteristics Analysis of an Assembly Robot for a Wine Box Base Considering Radial and Axial Clearances in a 3D Revolute Joint

open access: yesApplied Sciences, 2023
Precisely fitting the bottom sticker of the wine box base to the base model with glue is an important process of the wine box base production line. The influence of joint clearance in the assembly robot on the assembly precision of wine box bases is ...
Yuan Wang   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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