Results 51 to 60 of about 3,784,270 (306)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Sliding Mode Contact Force Control of n-Dof Robotics by Force Estimation
Majlesi Journal of Electrical EngineeringControl of the force exerted on an object is important for boosting system performance in robotics manipulators. Any undesired applied force may leave remarkable effects on the system, with the potential to damage the object.
Majid Namnabat +2 more
doaj +1 more source
Applied Sciences, 2023 Precisely fitting the bottom sticker of the wine box base to the base model with glue is an important process of the wine box base production line. The influence of joint clearance in the assembly robot on the assembly precision of wine box bases is ...
Yuan Wang +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
On Electromotive Forces of Contact [PDF]
Proceedings of the Physical Society of London, 1887 n ...
openaire +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Scientific ReportsAiming at the three-body contact problem of mechanical rough surface containing wet coal dust interface, the three-body contact model of rough surface containing wet coal dust interface is constructed by comprehensively considering the contact ...
Xinwei Yang +4 more
doaj +1 more source
Chengshi guidao jiaotong yanjiuObjective Contact force is a crucial aspect of comprehensive detection in the rail transit PC (pantograph-catenary) system and serves as an important evaluation factor of PC system performance.
YANG Jinsong +5 more
doaj +1 more source
Explicit Dynamic DDA Method considering Dynamic Contact Force
Shock and Vibration, 2016 This paper proposes an explicit dynamic DDA method considering dynamic contact force, which aims at solving the problems of low efficiency of dynamic contact detection and the simulation of dynamic contact force in the conventional DDA method. The mutual
Jian Zhao +3 more
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source