Results 71 to 80 of about 3,784,270 (306)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Measuring cell adhesion forces with the atomic force microscope at the molecular level [PDF]

open access: yes, 2002
In the past 25 years many techniques have been developed to characterize cell adhesion and to quantify adhesion forces. Atomic force microscopy (AFM) has been used to measure forces in the pico-newton range, an experimental technique known as force ...
Benoit, M., Gaub, H. E.
core   +1 more source

A contact-force regulated photoplethysmography (PPG) platform

open access: yesAIP Advances, 2018
A photoplethysmography (PPG) platform integrated with a miniaturized force-regulator is proposed in this study. Because a thermo-pneumatic type regulator maintains a consistent contact-force between the PPG probe and the measuring site, a consistent and ...
Jai Kyoung Sim, Bongyoung Ahn, Il Doh
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Comparative Study on Calculation Method of Contact Force in Joint with Clearance of Crank Slider Mechanism

open access: yesJixie chuandong, 2021
In order to select the best contact force calculation method for the dynamics performance analysis of multibody systems involving joints with clearance, a dynamics model of a crank slider mechanism involving joints with clearance is established and a ...
Tingting Li   +3 more
doaj  

Arches and contact forces in a granular pile [PDF]

open access: yesThe European Physical Journal E, 2012
7 pages, 7 figures, major ...
Carlevaro, Carlos Manuel   +1 more
openaire   +4 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Study on reducing ball force fluctuation of Rzeppa constant velocity joint

open access: yesNihon Kikai Gakkai ronbunshu, 2020
Rzeppa constant velocity joints are mainly used as outboard joints in the drive-shafts of front wheel drive vehicles. This type of joint transmits driving torque through balls provided in the joint.
Hideki SUGIURA   +2 more
doaj   +1 more source

Oblique penetration mechanism of hybrid composite laminates

open access: yesScience and Engineering of Composite Materials, 2021
Hybrid fiber composites are widely used to improve the anti-penetration performance. Carbon/Kevlar hybrid composites are used in aircrafts and safety devices, thanks to the strong toughness of Kevlar fibers and high strength of carbon fibers.
Han Meng   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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