Results 61 to 70 of about 432,503 (265)
A contact-force regulated photoplethysmography (PPG) platform
AIP Advances, 2018 A photoplethysmography (PPG) platform integrated with a miniaturized force-regulator is proposed in this study. Because a thermo-pneumatic type regulator maintains a consistent contact-force between the PPG probe and the measuring site, a consistent and ...
Jai Kyoung Sim, Bongyoung Ahn, Il Doh
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Jixie chuandong, 2021 In order to select the best contact force calculation method for the dynamics performance analysis of multibody systems involving joints with clearance， a dynamics model of a crank slider mechanism involving joints with clearance is established and a ...
Tingting Li +3 more
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Arches and contact forces in a granular pile [PDF]
The European Physical Journal E, 2012 7 pages, 7 figures, major ...
Carlevaro, Carlos Manuel +1 more
openaire +4 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Sensors, 2013 A study of the operator contact force influence on the performance of Articulated Arm Coordinate Measuring Machines (AACMMs) is presented in this paper. After developing a sensor capable of measuring the contact force applied by an operator, a ring gauge
Joaquín Barreiro +3 more
doaj +1 more source
Study on reducing ball force fluctuation of Rzeppa constant velocity joint
Nihon Kikai Gakkai ronbunshu, 2020 Rzeppa constant velocity joints are mainly used as outboard joints in the drive-shafts of front wheel drive vehicles. This type of joint transmits driving torque through balls provided in the joint.
Hideki SUGIURA +2 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source