Results 31 to 40 of about 29,094 (266)

A study of normal dynamic parameter models of joint interfaces based on fractal theory

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2015
The dynamic behaviors of the joint interfaces make a great difference in machine tools, especially in high-end numerical control machines. To provide an assessment of the normal dynamic parameters in contact deformation of elastoplastic solid joint ...
Wenwei LIU, Jiajun YANG, Neng XI, Jingfang SHEN, Linlin LI   +4 more
doaj   +1 more source

On the Mechanism of Cavitation Damage by Nonhemispherical Cavities Collapsing in Contact With a Solid Boundary [PDF]

Journal of Basic Engineering, 1961
A perfect fluid theory, which neglects the effect of gravity, and which assumes that the pressure inside a cavitation bubble remains constant during the collapse process, is given for the case of a nonhemispherical, but axially symmetric cavity which collapses in contact with a solid boundary.
Naudé, Charl F., Ellis, Albert T.
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Basic Principle and Contact Analysis of Internal Meshing Gear Drive with Curve Configuration

Jixie chuandong, 2022
Based on gear transmission conjugate-curve theory research， taking the internal meshing gear transmission with curve element as the object， general meshing equation of spatial conjugate curves along the designated contact angle position is derived and ...
Dong Liang, Sheng Meng, Ming Li, Xiangyang Xu, Zeyin He   +4 more
doaj  

Analysis of an Elasto-Hydrodynamic Seal by Using the Reynolds Equation

Applied Sciences, 2022
This paper reports numerical studies of an Elasto-Hydrodynamic (EHD) seal, which is being developed for supercritical CO2 (sCO2) turbomachinery applications. Current sCO2 turbomachinery suffers from high leakage rates, which is creating a major roadblock
Sevki Cesmeci, Karthik Reddy Lyathakula, Mohammad Fuad Hassan, Shuangbiao Liu, Hanping Xu, Jing Tang   +5 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Tykhonov well-posedness of fixed point problems in contact mechanics

Fixed Point Theory and Algorithms for Sciences and Engineering, 2022
We consider a fixed point problem S u = u $\mathcal {S}u=u$ where S : C ( R + ; X ) → C ( R + ; X ) ${\mathcal {S}:C(\mathbb{R}_{+};X)\to C(\mathbb{R}_{+};X)}$ is an almost history-dependent operator.
Mircea Sofonea
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Two-Step Growth Mechanism of the Solid Electrolyte Interphase in Argyrodyte/Li-Metal Contacts

ACS Applied Materials & Interfaces
The structure and growth of the solid electrolyte interphase (SEI) region between an electrolyte and an electrode is one of the most fundamental yet less well-understood phenomena in solid-state batteries. We present an atomistic simulation of the SEI growth for one of the currently promising solid electrolytes (Li6PS5Cl), based on ab initio-trained ...
Gracie Chaney, Andrey Golov, Ambroise van Roekeghem, Javier Carrasco, Natalio Mingo   +4 more
openaire   +4 more sources