Results 101 to 110 of about 35,737,382 (164)
Neuromyotonia and CASPR2 Antibodies: Electrophysiological Clues to Disease Pathophysiology
Contactin-associated protein-like 2 (CASPR2) is a transmembrane protein of the neurexin superfamily, essential for clustering voltage-gated potassium channels, particularly Kv1, at the juxtaparanodal regions of myelinated axons. This precise localisation
João Moura +5 more
doaj +1 more source
Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia.
BACKGROUND: Relatively few studies have searched for potentially pathogenic antibodies in non-paraneoplastic patients with cerebellar ataxia. METHODS AND RESULTS: We first screened sera from 52 idiopathic ataxia patients for binding of serum IgG ...
Robertson, Neil +24 more
core +2 more sources
Immune-mediated epilepsy (IME) constitutes a substantial proportion of drug-refractory epilepsies. Rapid diagnosis and prompt immunosuppression are required along with antiseizure medications (ASMs).
Aakash Mahesan +6 more
doaj +1 more source
Migratory vasodilatation of cerebral arteries in MELAS episodes: a case report and literature review
Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) is the commonest inherited mitochondrial disorder. Dilation of the major cerebral arteries is seldom mentioned in MELAS because magnetic resonance angiography (MRA ...
Ying Luo +13 more
doaj +1 more source
MOG-AD and CASPR2 Encephalitis (Overlap Syndrome) in an Adolescent Girl: A Case Report
Background: Although myelin oligodendrocytes glycoprotein antibody-associated disease (MOG-AD) and anti-contactin-associated protein-like 2 (CASPR2) antibody-mediated encephalitis are distinct neurological disorders, combined existence has rarely been ...
Dona Teresa Thomas +4 more
doaj +1 more source
Specialized paranodal junctions form between the axon and the closely apposed paranodal loops of myelinating glia. They are interposed between sodium channels at the nodes of Ranvier and potassium channels in the juxtaparanodal regions; their precise ...
Martin Grumet +7 more
core +1 more source
Leucine-rich Glioma-inactivated 1 Encephalitis Followed by Isaacs Syndrome: Alternating Presence of Pathogenic Autoantibodies to Leucine-rich Glioma-inactivated 1 and Contactin-associated Protein-like 2. [PDF]
Murayama A +6 more
europepmc +1 more source

